Transcriptome profiling of bovine ovarian theca cells treated with fibroblast growth factor 9

We reported previously that fibroblast growth factor 9 (FGF9) acts as an antidifferentiation factor, stimulating proliferation of granulosa cells (GCs) and theca cells (TCs) while suppressing hormone-induced steroidogenesis of these cells. How FGF9 acts to simultaneously suppress steroidogenesis and...

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Veröffentlicht in:	Domestic animal endocrinology 2018-04, Vol.63, p.48-58
Hauptverfasser:	Schütz, L.F., Hurst, R.E., Schreiber, N.B., Spicer, L.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beef cattle Cattle Cell proliferation computer software Down-Regulation Female Fibroblast Growth Factor 9 - pharmacology Fibroblast growth factor-9 (FGF9) fibroblast growth factors follicular development gene expression regulation Gene Expression Regulation - drug effects genes granulosa cells insulin-like growth factor I luteinizing hormone Microarray microarray technology Protein Array Analysis RNA slaughterhouses Steroidogenesis Theca cell Theca Cells - drug effects Theca Cells - metabolism transcriptome transcriptomics Up-Regulation
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