Hepatocyte specific expression of an oncogenic variant of β-catenin results in lethal metabolic dysfunction in mice

Wnt/β-catenin signaling plays a crucial role in embryogenesis, tissue homeostasis, metabolism and malignant transformation of different organs including the liver. Continuous β-catenin signaling due to somatic mutations in exon 3 of the gene is associated with different liver diseases including canc...

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Veröffentlicht in:	Oncotarget 2018-02, Vol.9 (13), p.11243-11257
Hauptverfasser:	Lemberger, Ursula J, Fuchs, Claudia D, Schöfer, Christian, Bileck, Andrea, Gerner, Christopher, Stojakovic, Tatjana, Taketo, Makoto M, Trauner, Michael, Egger, Gerda, Österreicher, Christoph H
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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