Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies

Previous studies have reported the prognostic impact of primary tumor sidedness in metastatic colorectal cancer (mCRC) and its influence on cetuximab efficacy. The present retrospective analysis of two panitumumab trials investigated a possible association between tumor sidedness and treatment effic...

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Veröffentlicht in:	Annals of oncology 2017-08, Vol.28 (8), p.1862-1868
Hauptverfasser:	Boeckx, N., Koukakis, R., Op de Beeck, K., Rolfo, C., Van Camp, G., Siena, S., Tabernero, J., Douillard, J.-Y., André, T., Peeters, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies, Monoclonal - therapeutic use Antineoplastic Agents, Immunological - therapeutic use Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Female first-line Genes, ras Humans Male metastatic colorectal cancer Middle Aged Neoplasm Metastasis Original Panitumumab Prognosis Randomized Controlled Trials as Topic RAS wild-type Retrospective Studies Survival Analysis Treatment Outcome tumor sidedness
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