Antibody-mediated thyroid dysfunction during T-cell checkpoint blockade in patients with non-small-cell lung cancer

Programmed cell death protein-1 (PD-1) blockade therapies have demonstrated durable responses and prolonged survival in a variety of malignancies. Treatment is generally well tolerated although immune-related adverse events (irAEs) can occur. Autoimmune thyroid dysfunction is among the most common i...

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Veröffentlicht in:Annals of oncology 2017-03, Vol.28 (3), p.583-589
Hauptverfasser: Osorio, J.C., Ni, A., Chaft, J.E., Pollina, R., Kasler, M.K., Stephens, D., Rodriguez, C., Cambridge, L., Rizvi, H., Wolchok, J.D., Merghoub, T., Rudin, C.M., Fish, S., Hellmann, M.D.
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Sprache:eng
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