Role of autophagy in modulating post-maturation aging of mouse oocytes

Mechanisms for post-maturation oocyte aging (PMOA) are not fully understood, and whether autophagy plays any role in PMOA is unknown. To explore the role of autophagy in PMOA, expression of autophagosomes and effects of the autophagy (macro-autophagy) activity on PMOA were observed in mouse oocytes....

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Veröffentlicht in:	Cell death & disease 2018-02, Vol.9 (3), p.308-12, Article 308
Hauptverfasser:	Lin, Fei-Hu, Zhang, Wei-Ling, Li, Hong, Tian, Xiao-Dan, Zhang, Jie, Li, Xiao, Li, Chuan-Yong, Tan, Jing-He
Format:	Artikel
Sprache:	eng
Schlagworte:	13/2 13/51 14/19 82/1 82/80 Aging Aging - metabolism Animals Antibodies Apoptosis Autophagy Biochemistry Biomedical and Life Sciences Calcium Caspase Caspase 3 - genetics Caspase 3 - metabolism Caspase-3 Cell Biology Cell Culture Cortex Cytoplasm - genetics Cytoplasm - metabolism Female Immunology Life Sciences Lithium Lithium chloride Maturation Membrane potential Mice Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Mitochondria Oocytes Oocytes - cytology Oocytes - metabolism Oxidative stress Phagocytosis Phagosomes Rapamycin
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