Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells

Aims Blue light is an identified risk factor for age-related macular degeneration (AMD). We investigated oxidative stress markers and mitochondrial changes in A2E-loaded retinal pigment epithelium cells under the blue–green part of the solar spectrum that reaches the retina to better understand the...

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Veröffentlicht in:	Cell death & disease 2018-02, Vol.9 (3), p.287-13, Article 287
Hauptverfasser:	Marie, Mélanie, Bigot, Karine, Angebault, Claire, Barrau, Coralie, Gondouin, Pauline, Pagan, Delphine, Fouquet, Stéphane, Villette, Thierry, Sahel, José-Alain, Lenaers, Guy, Picaud, Serge
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/106 14/19 38/90 82/51 Aging Antibodies Antioxidants Biochemistry Biomedical and Life Sciences Catalase Cell Biology Cell Culture Cellular Biology Epithelium Eyes & eyesight Gene expression Glutathione Human health and pathology Hydrogen peroxide Illumination Immunology Life Sciences Light Macular degeneration Membrane potential Mitochondria Oxidation Oxidative stress Reactive oxygen species Retina Retinal pigment epithelium Sensory Organs Subcellular Processes Superoxide dismutase Toxicity
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