TADs are 3D structural units of higher-order chromosome organization in Drosophila

Deciphering the rules of genome folding in the cell nucleus is essential to understand its functions. Recent chromosome conformation capture (Hi-C) studies have revealed that the genome is partitioned into topologically associating domains (TADs), which demarcate functional epigenetic domains define...

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Veröffentlicht in:	Science advances 2018-02, Vol.4 (2), p.eaar8082-eaar8082
Hauptverfasser:	Szabo, Quentin, Jost, Daniel, Chang, Jia-Ming, Cattoni, Diego I, Papadopoulos, Giorgio L, Bonev, Boyan, Sexton, Tom, Gurgo, Julian, Jacquier, Caroline, Nollmann, Marcelo, Bantignies, Frédéric, Cavalli, Giacomo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biopolymers - chemistry Chromatin - chemistry Chromosomes, Insect - chemistry Chromosomes, Insect - genetics Drosophila - genetics Genetics Imaging, Three-Dimensional Life Sciences Molecular Biology Nanoparticles - chemistry SciAdv r-articles
Online-Zugang:	Volltext
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