The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities

The NM23/NME gene was identified as a metastasis suppressor. It's re-expression inhibited cancer cell motility and suppressed metastasis, without effecting primary tumor size in multiple model systems. The mechanisms of NME suppression of motility and metastasis are incompletely known. Of parti...

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Veröffentlicht in:	Oncotarget 2018-02, Vol.9 (12), p.10185-10202
Hauptverfasser:	Khan, Imran, Steeg, Patricia S
Format:	Artikel
Sprache:	eng
Schlagworte:	Priority Research Paper
Online-Zugang:	Volltext
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