Conserved and Divergent Features of Human and Mouse Kidney Organogenesis

Human kidney function is underpinned by approximately 1,000,000 nephrons, although the number varies substantially, and low nephron number is linked to disease. Human kidney development initiates around 4 weeks of gestation and ends around 34-37 weeks of gestation. Over this period, a reiterative in...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2018-03, Vol.29 (3), p.785-805
Hauptverfasser:	Lindström, Nils O, McMahon, Jill A, Guo, Jinjin, Tran, Tracy, Guo, Qiuyu, Rutledge, Elisabeth, Parvez, Riana K, Saribekyan, Gohar, Schuler, Robert E, Liao, Christopher, Kim, Albert D, Abdelhalim, Ahmed, Ruffins, Seth W, Thornton, Matthew E, Baskin, Laurence, Grubbs, Brendan, Kesselman, Carl, McMahon, Andrew P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Research Cell Differentiation Fluorescent Antibody Technique Gene Expression Profiling Gestational Age Histological Techniques Humans In Situ Hybridization Kidney - anatomy & histology Kidney - embryology Kidney - metabolism Mice Nephrons - embryology Nephrons - metabolism Organogenesis RNA - analysis Ureter - embryology Ureter - metabolism
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