Population Pharmacokinetics of Polymyxin B in Acutely Ill Adult Patients

Polymyxin B (PB) has reemerged as a common treatment against multidrug-resistant Gram-negative pathogens. However, nephrotoxicity remains a significant dose-limiting side effect, and contemporary pharmacokinetic (PK) data are limited. This study sought to evaluate PB exposure differences in various...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2018-03, Vol.62 (3)
Hauptverfasser:	Miglis, Cristina, Rhodes, Nathaniel J, Avedissian, Sean N, Kubin, Christine J, Yin, Michael T, Nelson, Brian C, Pai, Manjunath P, Scheetz, Marc H
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Comment On Pharmacology Polymyxin B
Online-Zugang:	Volltext
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