Fermentation Conditions and Media Optimization for Isocitric Acid Production from Ethanol by Yarrowia lipolytica

Isocitric acid exists in the form of four stereoisomers, of which only the threo-Ds-form (ICA) is a natural active compound, an intermediate of Krebs cycle, and suitable for nutritional and pharmaceutical use. In this paper, we propose a method for ICA production from ethanol by yeast Yarrowia lipol...

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Veröffentlicht in:	BioMed research international 2018-01, Vol.2018 (2018), p.1-9
Hauptverfasser:	Morgunov, Igor G., Allayarov, Ramil K., Lunina, Julia N., Morgunov, Grigorii I., Stepanova, Nadezda N., Shamin, Roman V., Kamzolova, Svetlana V., Samoilenko, Vladimir A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid production Acids Aeration Alcohol Alcohol, Denatured Baking yeast Biochemistry Biotechnology Carbon Chemical synthesis Citric Acid Cycle Cultivation Culture media Culture Media - chemistry Diastereomers Energy Ethanol Ethanol - chemistry Ethanol - metabolism Fermentation Hydrogen ions Hypoxia Iron Isocitrate lyase Isocitrate Lyase - chemistry Isocitrates - chemistry Isocitric acid Itaconic acid Kinases Krebs cycle Lipids Metabolism Metabolites Microbiology Microorganisms Nutrient content Nutrition Optimization Oxygen - chemistry pH effects Physiological aspects Production processes Respiration Saccharomyces cerevisiae Saturation Stereoisomerism Stereoisomers Temperature effects Tricarboxylic acid cycle Yarrowia - chemistry Yarrowia lipolytica Zinc
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