Genes linked to species diversity in a sexually dimorphic communication signal in electric fish
Sexually dimorphic behaviors are often regulated by androgens and estrogens. Steroid receptors and metabolism are control points for evolutionary changes in sexual dimorphism. Electric communication signals of South American knifefishes are a model for understanding the evolution and physiology of s...
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| Veröffentlicht in: | Journal of Comparative Physiology 2018-01, Vol.204 (1), p.93-112 |
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| creator | Smith, G. Troy Proffitt, Melissa R. Smith, Adam R. Rusch, Douglas B. |
| description | Sexually dimorphic behaviors are often regulated by androgens and estrogens. Steroid receptors and metabolism are control points for evolutionary changes in sexual dimorphism. Electric communication signals of South American knifefishes are a model for understanding the evolution and physiology of sexually dimorphic behavior. These signals are regulated by gonadal steroids and controlled by a simple neural circuit. Sexual dimorphism of the signals varies across species. We used transcriptomics to examine mechanisms for sex differences in electric organ discharges (EODs) of two closely related species,
Apteronotus leptorhynchus
and
Apteronotus albifrons
, with reversed sexual dimorphism in their EODs. The pacemaker nucleus (Pn), which controls EOD frequency (EODf), expressed transcripts for steroid receptors and metabolizing enzymes, including androgen receptors, estrogen receptors, aromatase, and 5α-reductase. The Pn expressed mRNA for ion channels likely to regulate the high-frequency activity of Pn neurons and for neuromodulator and neurotransmitter receptors that may regulate EOD modulations used in aggression and courtship. Expression of several ion channel genes, including those for Kir3.1 inward-rectifying potassium channels and sodium channel β1 subunits, was sex-biased or correlated with EODf in ways consistent with EODf sex differences. Our findings provide a basis for future studies to characterize neurogenomic mechanisms by which sex differences evolve. |
| doi_str_mv | 10.1007/s00359-017-1223-3 |
| format | Article |
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Apteronotus leptorhynchus
and
Apteronotus albifrons
, with reversed sexual dimorphism in their EODs. The pacemaker nucleus (Pn), which controls EOD frequency (EODf), expressed transcripts for steroid receptors and metabolizing enzymes, including androgen receptors, estrogen receptors, aromatase, and 5α-reductase. The Pn expressed mRNA for ion channels likely to regulate the high-frequency activity of Pn neurons and for neuromodulator and neurotransmitter receptors that may regulate EOD modulations used in aggression and courtship. Expression of several ion channel genes, including those for Kir3.1 inward-rectifying potassium channels and sodium channel β1 subunits, was sex-biased or correlated with EODf in ways consistent with EODf sex differences. Our findings provide a basis for future studies to characterize neurogenomic mechanisms by which sex differences evolve.</description><identifier>ISSN: 0340-7594</identifier><identifier>EISSN: 1432-1351</identifier><identifier>DOI: 10.1007/s00359-017-1223-3</identifier><identifier>PMID: 29058069</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>aggression ; Androgen receptors ; Androgens ; Animal Physiology ; Apteronotus albifrons ; Apteronotus leptorhynchus ; Aromatase ; Biodiversity ; Biomedical and Life Sciences ; Courtship ; Electric communication ; Estrogen receptors ; Estrogens ; evolution ; fish ; Gender aspects ; Gender differences ; Gene expression ; Genes ; gonads ; Ion channels ; Life Sciences ; messenger RNA ; Metabolism ; neural networks ; Neuromodulation ; neurons ; Neurosciences ; Neurotransmitter receptors ; Original Paper ; Potassium ; Potassium channels ; Potassium channels (inwardly-rectifying) ; Receptors ; Sex ; Sex differences ; Sex hormones ; Sexual behavior ; Sexual dimorphism ; Sodium ; sodium channels ; Species diversity ; Steroid 5α-reductase ; Steroid hormone receptors ; Steroids ; transcriptomics ; Zoology</subject><ispartof>Journal of Comparative Physiology, 2018-01, Vol.204 (1), p.93-112</ispartof><rights>Springer-Verlag GmbH Germany 2017</rights><rights>Journal of Comparative Physiology A is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-42c8f3f4e1e38a0d165cb65b99dd5c67658b496a0894472c111fe146c3369f6e3</citedby><cites>FETCH-LOGICAL-c503t-42c8f3f4e1e38a0d165cb65b99dd5c67658b496a0894472c111fe146c3369f6e3</cites><orcidid>0000-0001-6930-7105</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00359-017-1223-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00359-017-1223-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27915,27916,41479,42548,51310</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29058069$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smith, G. Troy</creatorcontrib><creatorcontrib>Proffitt, Melissa R.</creatorcontrib><creatorcontrib>Smith, Adam R.</creatorcontrib><creatorcontrib>Rusch, Douglas B.</creatorcontrib><title>Genes linked to species diversity in a sexually dimorphic communication signal in electric fish</title><title>Journal of Comparative Physiology</title><addtitle>J Comp Physiol A</addtitle><addtitle>J Comp Physiol A Neuroethol Sens Neural Behav Physiol</addtitle><description>Sexually dimorphic behaviors are often regulated by androgens and estrogens. Steroid receptors and metabolism are control points for evolutionary changes in sexual dimorphism. Electric communication signals of South American knifefishes are a model for understanding the evolution and physiology of sexually dimorphic behavior. These signals are regulated by gonadal steroids and controlled by a simple neural circuit. Sexual dimorphism of the signals varies across species. We used transcriptomics to examine mechanisms for sex differences in electric organ discharges (EODs) of two closely related species,
Apteronotus leptorhynchus
and
Apteronotus albifrons
, with reversed sexual dimorphism in their EODs. The pacemaker nucleus (Pn), which controls EOD frequency (EODf), expressed transcripts for steroid receptors and metabolizing enzymes, including androgen receptors, estrogen receptors, aromatase, and 5α-reductase. The Pn expressed mRNA for ion channels likely to regulate the high-frequency activity of Pn neurons and for neuromodulator and neurotransmitter receptors that may regulate EOD modulations used in aggression and courtship. Expression of several ion channel genes, including those for Kir3.1 inward-rectifying potassium channels and sodium channel β1 subunits, was sex-biased or correlated with EODf in ways consistent with EODf sex differences. Our findings provide a basis for future studies to characterize neurogenomic mechanisms by which sex differences evolve.</description><subject>aggression</subject><subject>Androgen receptors</subject><subject>Androgens</subject><subject>Animal Physiology</subject><subject>Apteronotus albifrons</subject><subject>Apteronotus leptorhynchus</subject><subject>Aromatase</subject><subject>Biodiversity</subject><subject>Biomedical and Life Sciences</subject><subject>Courtship</subject><subject>Electric communication</subject><subject>Estrogen receptors</subject><subject>Estrogens</subject><subject>evolution</subject><subject>fish</subject><subject>Gender aspects</subject><subject>Gender differences</subject><subject>Gene expression</subject><subject>Genes</subject><subject>gonads</subject><subject>Ion channels</subject><subject>Life Sciences</subject><subject>messenger RNA</subject><subject>Metabolism</subject><subject>neural networks</subject><subject>Neuromodulation</subject><subject>neurons</subject><subject>Neurosciences</subject><subject>Neurotransmitter receptors</subject><subject>Original Paper</subject><subject>Potassium</subject><subject>Potassium channels</subject><subject>Potassium channels (inwardly-rectifying)</subject><subject>Receptors</subject><subject>Sex</subject><subject>Sex differences</subject><subject>Sex hormones</subject><subject>Sexual behavior</subject><subject>Sexual dimorphism</subject><subject>Sodium</subject><subject>sodium channels</subject><subject>Species diversity</subject><subject>Steroid 5α-reductase</subject><subject>Steroid hormone receptors</subject><subject>Steroids</subject><subject>transcriptomics</subject><subject>Zoology</subject><issn>0340-7594</issn><issn>1432-1351</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkU2LFDEQhoMo7rj6A7xIgxcvral8dXIRZNFVWPCi55BJV89k7U7GpHvZ-femmXVZBfEUqHrqTVIPIS-BvgVKu3eFUi5NS6FrgTHe8kdkA4KzFriEx2RDuaBtJ404I89KuaaUMmDwlJwxQ6WmymyIvcSIpRlD_IF9M6emHNCHWunDDeYS5mMTYuOagreLG8djrU8pH_bBNz5N0xKDd3NIsSlhF924wjiin3MFhlD2z8mTwY0FX9yd5-T7p4_fLj63V18vv1x8uGq9pHxuBfN64INAQK4d7UFJv1Vya0zfS686JfVWGOWoNkJ0zAPAgCCU51yZQSE_J-9PuYdlO2HvMc7ZjfaQw-Ty0SYX7J-dGPZ2l26s1NBpbWrAm7uAnH4uWGY7heJxHF3EtBTLqFhXBpr-FwUjhWBKi66ir_9Cr9OS66JWynDZgaSqUnCifE6lZBzu3w3UrqbtybStpu1q2vI68-rhh-8nfqutADsBpbbiDvODq_-Z-guN0bQN</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Smith, G. Troy</creator><creator>Proffitt, Melissa R.</creator><creator>Smith, Adam R.</creator><creator>Rusch, Douglas B.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QR</scope><scope>7SS</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-6930-7105</orcidid></search><sort><creationdate>20180101</creationdate><title>Genes linked to species diversity in a sexually dimorphic communication signal in electric fish</title><author>Smith, G. Troy ; Proffitt, Melissa R. ; Smith, Adam R. ; Rusch, Douglas B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-42c8f3f4e1e38a0d165cb65b99dd5c67658b496a0894472c111fe146c3369f6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>aggression</topic><topic>Androgen receptors</topic><topic>Androgens</topic><topic>Animal Physiology</topic><topic>Apteronotus albifrons</topic><topic>Apteronotus leptorhynchus</topic><topic>Aromatase</topic><topic>Biodiversity</topic><topic>Biomedical and Life Sciences</topic><topic>Courtship</topic><topic>Electric communication</topic><topic>Estrogen receptors</topic><topic>Estrogens</topic><topic>evolution</topic><topic>fish</topic><topic>Gender aspects</topic><topic>Gender differences</topic><topic>Gene expression</topic><topic>Genes</topic><topic>gonads</topic><topic>Ion channels</topic><topic>Life Sciences</topic><topic>messenger RNA</topic><topic>Metabolism</topic><topic>neural networks</topic><topic>Neuromodulation</topic><topic>neurons</topic><topic>Neurosciences</topic><topic>Neurotransmitter receptors</topic><topic>Original Paper</topic><topic>Potassium</topic><topic>Potassium channels</topic><topic>Potassium channels (inwardly-rectifying)</topic><topic>Receptors</topic><topic>Sex</topic><topic>Sex differences</topic><topic>Sex hormones</topic><topic>Sexual behavior</topic><topic>Sexual dimorphism</topic><topic>Sodium</topic><topic>sodium channels</topic><topic>Species diversity</topic><topic>Steroid 5α-reductase</topic><topic>Steroid hormone receptors</topic><topic>Steroids</topic><topic>transcriptomics</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Smith, G. Troy</creatorcontrib><creatorcontrib>Proffitt, Melissa R.</creatorcontrib><creatorcontrib>Smith, Adam R.</creatorcontrib><creatorcontrib>Rusch, Douglas B.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Comparative Physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Smith, G. Troy</au><au>Proffitt, Melissa R.</au><au>Smith, Adam R.</au><au>Rusch, Douglas B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genes linked to species diversity in a sexually dimorphic communication signal in electric fish</atitle><jtitle>Journal of Comparative Physiology</jtitle><stitle>J Comp Physiol A</stitle><addtitle>J Comp Physiol A Neuroethol Sens Neural Behav Physiol</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>204</volume><issue>1</issue><spage>93</spage><epage>112</epage><pages>93-112</pages><issn>0340-7594</issn><eissn>1432-1351</eissn><abstract>Sexually dimorphic behaviors are often regulated by androgens and estrogens. Steroid receptors and metabolism are control points for evolutionary changes in sexual dimorphism. Electric communication signals of South American knifefishes are a model for understanding the evolution and physiology of sexually dimorphic behavior. These signals are regulated by gonadal steroids and controlled by a simple neural circuit. Sexual dimorphism of the signals varies across species. We used transcriptomics to examine mechanisms for sex differences in electric organ discharges (EODs) of two closely related species,
Apteronotus leptorhynchus
and
Apteronotus albifrons
, with reversed sexual dimorphism in their EODs. The pacemaker nucleus (Pn), which controls EOD frequency (EODf), expressed transcripts for steroid receptors and metabolizing enzymes, including androgen receptors, estrogen receptors, aromatase, and 5α-reductase. The Pn expressed mRNA for ion channels likely to regulate the high-frequency activity of Pn neurons and for neuromodulator and neurotransmitter receptors that may regulate EOD modulations used in aggression and courtship. Expression of several ion channel genes, including those for Kir3.1 inward-rectifying potassium channels and sodium channel β1 subunits, was sex-biased or correlated with EODf in ways consistent with EODf sex differences. Our findings provide a basis for future studies to characterize neurogenomic mechanisms by which sex differences evolve.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29058069</pmid><doi>10.1007/s00359-017-1223-3</doi><tpages>20</tpages><orcidid>https://orcid.org/0000-0001-6930-7105</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | aggression Androgen receptors Androgens Animal Physiology Apteronotus albifrons Apteronotus leptorhynchus Aromatase Biodiversity Biomedical and Life Sciences Courtship Electric communication Estrogen receptors Estrogens evolution fish Gender aspects Gender differences Gene expression Genes gonads Ion channels Life Sciences messenger RNA Metabolism neural networks Neuromodulation neurons Neurosciences Neurotransmitter receptors Original Paper Potassium Potassium channels Potassium channels (inwardly-rectifying) Receptors Sex Sex differences Sex hormones Sexual behavior Sexual dimorphism Sodium sodium channels Species diversity Steroid 5α-reductase Steroid hormone receptors Steroids transcriptomics Zoology |
| title | Genes linked to species diversity in a sexually dimorphic communication signal in electric fish |
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