Anxiety‐ and activity‐related effects of paracetamol on healthy and neuropathic rats

Paracetamol has recently been suggested to affect emotion processing in addition to alleviating pain in humans. We investigated in adult male Hannover–Wistar rats whether acute intraperitoneally administrated paracetamol affects behavior in tests measuring anxiety, mood, motor activity, and memory....

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Veröffentlicht in:	Pharmacology research & perspectives 2018-02, Vol.6 (1), p.n/a
Hauptverfasser:	Chen, Zuyue, Wei, Hong, Pertovaara, Antti, Wang, Jianhong, Carlson, Synnöve
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - pharmacology Acetaminophen - therapeutic use Analgesics anhedonia Animal cognition Animals Anti-Anxiety Agents - pharmacology Anti-Anxiety Agents - therapeutic use Anxiety Anxiety - drug therapy Anxiety - psychology Behavior, Animal - drug effects Disease Models, Animal Dose-Response Relationship, Drug Human subjects Humans Hyperalgesia - drug therapy Hyperalgesia - etiology Hyperalgesia - psychology Injections, Intraperitoneal Laboratories Male Maze Learning - drug effects Motor Activity - drug effects Neuralgia - drug therapy Neuralgia - etiology Neuralgia - psychology neuropathic pain Original Pain paracetamol Pharmacology Rats Rats, Wistar recognition memory Sciatic Nerve - injuries Studies Treatment Outcome
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