Effect of increases in cardiac contractility on cerebral blood flow in humans

The effect of acute increases in cardiac contractility on cerebral blood flow (CBF) remains unknown. We hypothesized that the external carotid artery (ECA) downstream vasculature modifies the direct influence of acute increases in heart rate and cardiac function on CBF regulation. Twelve healthy sub...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2017-12, Vol.313 (6), p.H1155-H1161
Hauptverfasser:	Ogoh, Shigehiko, Moralez, Gilbert, Washio, Takuro, Sarma, Satyam, Hieda, Michinari, Romero, Steven A, Cramer, Matthew N, Shibasaki, Manabu, Crandall, Craig G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arterial Pressure - drug effects Arteries Blood flow Blood Flow Velocity Blood pressure Cardiac output Cardiac Output - drug effects Cardiotonic Agents - administration & dosage Carotid artery Carotid Artery, External - drug effects Carotid Artery, External - physiology Carotid Artery, Internal - drug effects Carotid Artery, Internal - physiology Cerebrovascular Circulation - drug effects Dobutamine - administration & dosage Dose-Response Relationship, Drug Drug dosages Echocardiography, Doppler External pressure Female Healthy Volunteers Heart rate Heart Rate - drug effects Humans Infusions, Intravenous Male Myocardial Contraction - drug effects Risk assessment Time Factors Ultrasonic imaging Veins & arteries Young Adult
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