Effects of repeated abobotulinumtoxinA injections in upper limb spasticity

ABSTRACT Introduction: The efficacy of single injections of abobotulinumtoxinA (Dysport) is established in adults with upper limb spasticity. In this study we assessed the effects of repeated injections of abobotulinumtoxinA over 1 year. Methods: Patients (n = 258, safety population) received 500 U,...

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Veröffentlicht in:	Muscle & nerve 2018-02, Vol.57 (2), p.245-254
Hauptverfasser:	Gracies, Jean‐Michel, O'Dell, Michael, Vecchio, Michele, Hedera, Peter, Kocer, Serdar, Rudzinska‐Bar, Monika, Rubin, Bruce, Timerbaeva, Sofiya L., Lusakowska, Anna, Boyer, François Constant, Grandoulier, Anne‐Sophie, Vilain, Claire, Picaut, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	active function Adult Adults Aged botulinum toxin Botulinum Toxins, Type A - administration & dosage Botulinum Toxins, Type A - adverse effects Botulinum Toxins, Type A - therapeutic use Clinical Research Disability Evaluation Double-Blind Method Elbow Elbow (anatomy) Elbow - physiopathology Female Fingers - physiopathology Flexors Humans Injections, Intramuscular Life Sciences Male Middle Aged Muscle Spasticity - drug therapy Muscle Spasticity - physiopathology Muscle Tonus - drug effects Muscles Neuromuscular Agents - administration & dosage Neuromuscular Agents - adverse effects Neuromuscular Agents - therapeutic use open label Range of Motion, Articular - drug effects Safety Spasticity stroke traumatic brain injury Treatment Outcome Upper Extremity - physiopathology upper limb spasticity Wrist Wrist - physiopathology
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