Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide

Current anti-hepatitis B virus (HBV) agents including interferons and nucleos(t)ide analogs efficiently suppress HBV infection. However, as it is difficult to eliminate HBV from chronically infected liver, alternative anti-HBV agents targeting a new molecule are urgently needed. In this study, we ap...

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Veröffentlicht in:	Scientific reports 2018-02, Vol.8 (1), p.2769-13, Article 2769
Hauptverfasser:	Kaneko, Manabu, Futamura, Yushi, Tsukuda, Senko, Kondoh, Yasumitsu, Sekine, Tomomi, Hirano, Hiroyuki, Fukano, Kento, Ohashi, Hirofumi, Saso, Wakana, Morishita, Ryo, Matsunaga, Satoko, Kawai, Fumihiro, Ryo, Akihide, Park, Sam-Yong, Suzuki, Ryosuke, Aizaki, Hideki, Ohtani, Naoko, Sureau, Camille, Wakita, Takaji, Osada, Hiroyuki, Watashi, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/106 631/326/22/1295 692/4020/4021/234/2513/1549 Bile Cell culture Coumarin Cytotoxicity Hepatitis Hepatitis B Hepatitis C Hepatocytes High-throughput screening Humanities and Social Sciences Infections Interferon Life Sciences Liver Microbiology and Parasitology multidisciplinary Polypeptides Science Science (multidisciplinary) Sodium Virology Virus attachment
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