Enhancement of ovalbumin-specific Th1, Th2, and Th17 immune responses by amorphous silica nanoparticles

Nanomaterials present in cosmetics and food additives are used for industrial applications. However, their safety profile is unclear. Amorphous silica nanoparticles (nSPs) are a widely used nanomaterial and have been shown to induce inflammatory cytokines following intratracheal administration in mi...

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Veröffentlicht in:	International journal of immunopathology and pharmacology 2016-09, Vol.29 (3), p.408-420
Hauptverfasser:	Toda, Tsuguto, Yoshino, Shin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvanticity Adjuvants Adjuvants, Immunologic - administration & dosage Allergic diseases Aluminum hydroxide Animals Antibodies - immunology Cosmetics Cytokines Environmental factors Food additives Helper cells Immune response Immunoglobulin G Immunoglobulin G - immunology Industrial applications Inflammation Injection Interleukin 17 Interleukin 2 Interleukin 4 Interleukin 5 Interleukin-17 - immunology Interleukin-17 - metabolism Lymphocytes T Male Mice Mice, Inbred BALB C Nanomaterials Nanoparticles Nanoparticles - administration & dosage Nanotechnology Original Ovalbumin Ovalbumin - administration & dosage Ovalbumin - immunology Particle Size Silicon Dioxide - administration & dosage Splenocytes Th1 Cells - drug effects Th1 Cells - immunology Th17 Cells - drug effects Th17 Cells - immunology Th2 Cells - drug effects Th2 Cells - immunology Trachea γ-Interferon
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