Age and diabetes related changes of the retinal capillaries: An ultrastructural and immunohistochemical study

Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system of elderly and diabetic patients. Current fin...

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Veröffentlicht in:	International journal of immunopathology and pharmacology 2016-03, Vol.29 (1), p.40-53
Hauptverfasser:	Bianchi, Enrica, Ripandelli, Guido, Taurone, Samanta, Feher, Janos, Plateroti, Rocco, Kovacs, Illes, Magliulo, Giuseppe, Orlando, Maria Patrizia, Micera, Alessandra, Battaglione, Ezio, Artico, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aging Aging - pathology Basement Membrane - pathology Capillaries Capillaries - pathology Capillaries - ultrastructure Central nervous system Child Cytokines Diabetes Diabetes mellitus Diabetic Retinopathy - pathology Endosomes Endothelial cells Female Fibrosis Geriatrics Glial cells Humans IL-1β Immunohistochemistry Inflammation Interleukin-6 - analysis Ischemia Lysosomes Male Microscopy Microscopy, Electron, Transmission Microvasculature Middle Aged Original Retina Retina - pathology Retina - ultrastructure Transmission electron microscopy Tumor Necrosis Factor-alpha - analysis Tumor necrosis factor-α Vascular endothelial growth factor Vascular Endothelial Growth Factor A - analysis
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