Whole-exome sequencing and gene-based rare variant association tests suggest that PLA2G4E might be a risk gene for panic disorder

Panic disorder (PD) is characterized by recurrent and unexpected panic attacks, subsequent anticipatory anxiety, and phobic avoidance. Recent epidemiological and genetic studies have revealed that genetic factors contribute to the pathogenesis of PD. We performed whole-exome sequencing on one Japane...

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Veröffentlicht in:	Translational psychiatry 2018-02, Vol.8 (1), p.41-8, Article 41
Hauptverfasser:	Morimoto, Yoshiro, Shimada-Sugimoto, Mihoko, Otowa, Takeshi, Yoshida, Shintaro, Kinoshita, Akira, Mishima, Hiroyuki, Yamaguchi, Naohiro, Mori, Takatoshi, Imamura, Akira, Ozawa, Hiroki, Kurotaki, Naohiro, Ziegler, Christiane, Domschke, Katharina, Deckert, Jürgen, Umekage, Tadashi, Tochigi, Mamoru, Kaiya, Hisanobu, Okazaki, Yuji, Tokunaga, Katsushi, Sasaki, Tsukasa, Yoshiura, Koh-ichiro, Ono, Shinji
Format:	Artikel
Sprache:	eng
Schlagworte:	45/23 631/208/1516 692/420/2489 Adult Behavioral Sciences Biological Psychology Case-Control Studies Female Genes Genetic Association Studies - methods Germany Group IV Phospholipases A2 - genetics Humans Japan Male Medicine Medicine & Public Health Neurosciences Panic attacks Panic Disorder - genetics Pedigree Pharmacotherapy Psychiatry Risk Whole Exome Sequencing - methods
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