Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice

Background: Obesity is associated with gut microbiota dysbiosis, disrupted intestinal barrier and chronic inflammation. Given the high and increasing prevalence of obesity worldwide, anti-obesity treatments that are safe, effective and widely available would be beneficial. We examined whether the me...

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Veröffentlicht in:	International Journal of Obesity 2018-02, Vol.42 (2), p.231-243
Hauptverfasser:	Chang, C-J, Lu, C-C, Lin, C-S, Martel, J, Ko, Y-F, Ojcius, D M, Wu, T-R, Tsai, Y-H, Yeh, T-S, Lu, J-J, Lai, H-C, Young, J D
Format:	Artikel
Sprache:	eng
Schlagworte:	13/95 631/250 631/326 631/92/349 64/60 692/4020/2741/2135 692/699/2743/393 692/700/459/1994 Accumulation Adiponectin Agaricales Animals Anti-inflammatory agents Antidiabetics Antrodia - chemistry Bacteria Body weight Complications and side effects Cytokines Development and progression Diabetes mellitus Diet Diet therapy Diet, High-Fat Dietary supplements Digestive system Disease Models, Animal Dysbacteriosis Dysbiosis - diet therapy Dysbiosis - physiopathology Edible mushrooms Endotoxemia Epidemiology Gastrointestinal Microbiome - drug effects Gastrointestinal tract Health aspects Health Promotion and Disease Prevention High fat diet Inflammation Inflammation - diet therapy Insulin Insulin Resistance - physiology Interleukin 6 Internal Medicine Intestinal microflora Leptin Lysozyme Male Markers Medicine Medicine & Public Health Medicine, Traditional Metabolic Diseases Mice Mice, Inbred C57BL Microbiota Microbiota (Symbiotic organisms) Obesity Obesity - diet therapy Obesity - physiopathology Original original-article Plant Extracts - pharmacology Plants, Medicinal - chemistry Prevention Proteins Public Health Resistance factors Risk factors Small intestine Statistical analysis Tight junctions Triglycerides Tumor necrosis factor-α Type 2 diabetes Weight reduction Zonula occludens-1 protein
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