Evaluation of PD-L1 expression on vortex-isolated circulating tumor cells in metastatic lung cancer

Metastatic non-small cell lung cancer (NSCLC) is a highly fatal and immunogenic malignancy. Although the immune system is known to recognize these tumor cells, one mechanism by which NSCLC can evade the immune system is via overexpression of programmed cell death ligand 1 (PD-L1). Recent clinical tr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2018-02, Vol.8 (1), p.2592-10, Article 2592
Hauptverfasser:	Dhar, Manjima, Wong, Jessica, Che, James, Matsumoto, Melissa, Grogan, Tristan, Elashoff, David, Garon, Edward B., Goldman, Jonathan W., Sollier Christen, Elodie, Di Carlo, Dino, Kulkarni, Rajan P.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/51 13/62 14/63 631/1647/277 631/67/1857 A549 Cells Adult Aged Aged, 80 and over Apoptosis B7-H1 Antigen - metabolism Biomarkers, Tumor - metabolism Biopsy Biopsy - methods Carcinoma, Non-Small-Cell Lung - secondary Carcinoma, Non-Small-Cell Lung - therapy Cell death Clinical trials Female HeLa Cells Heterogeneity Humanities and Social Sciences Humans Immune system Immunogenicity Immunotherapy Invasiveness Lung cancer Lung Neoplasms - pathology Lung Neoplasms - therapy Male Malignancy Metastases Metastasis Middle Aged multidisciplinary Neoplastic Cells, Circulating - drug effects Neoplastic Cells, Circulating - metabolism Non-small cell lung carcinoma PD-1 protein PD-L1 protein Precision medicine Science Science (multidisciplinary) Tumor cells Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!