Evaluation of Gamma-Radiation Inactivation of a Bioterrorism Agent, Bacillus anthracis Spores, on Different Materials
Decontamination of suspected packages, such as sealed envelopes, liquids and tools that are likely contaminated with biological agents is of great importance. In this study, we aimed to determine the gamma radiation dose required for the decontamination of paper, fabric and liquid materials without...
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| Veröffentlicht in: | Indian journal of microbiology 2018-03, Vol.58 (1), p.76-80 |
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| creator | Ortatatli, Mesut Canitez, Kadir Sezigen, Sermet Eyison, Ruşen Koray Kenar, Levent |
| description | Decontamination of suspected packages, such as sealed envelopes, liquids and tools that are likely contaminated with biological agents is of great importance. In this study, we aimed to determine the gamma radiation dose required for the decontamination of paper, fabric and liquid materials without causing any damage to the structure of these materials. Each study group included 11 pieces of paper, fabric and sterile saline contaminated with 0.8 × 10
5
virulent
Bacillus anthracis
(B.
anthracis
) spores. These specimens were exposed to doses of 5.49, 11.58, 17.21, 21.75, 27 and 33.1 kilogray (kGy) of gamma radiation from a cobalt-60 source. After irradiation of all the samples, a viability assessment of the B.
anthracis
spores was performed. It was found that full decontamination was achieved with 11.58 kGy on the paper samples and 17.21 kGy on the fabric and liquid samples. It was concluded that a dose of 20 kGy of gamma radiation may be recommended for the inactivation of B.
anthracis
for some surfaces when especially sensitive and valuable materials cannot be wet decontaminated were exposed. In addition, serologic and molecular assays of the suspected packets can be performed for forensic purposes without damaging existing evidence in a bioterror incident. |
| doi_str_mv | 10.1007/s12088-017-0691-z |
| format | Article |
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5
virulent
Bacillus anthracis
(B.
anthracis
) spores. These specimens were exposed to doses of 5.49, 11.58, 17.21, 21.75, 27 and 33.1 kilogray (kGy) of gamma radiation from a cobalt-60 source. After irradiation of all the samples, a viability assessment of the B.
anthracis
spores was performed. It was found that full decontamination was achieved with 11.58 kGy on the paper samples and 17.21 kGy on the fabric and liquid samples. It was concluded that a dose of 20 kGy of gamma radiation may be recommended for the inactivation of B.
anthracis
for some surfaces when especially sensitive and valuable materials cannot be wet decontaminated were exposed. In addition, serologic and molecular assays of the suspected packets can be performed for forensic purposes without damaging existing evidence in a bioterror incident.</description><identifier>ISSN: 0046-8991</identifier><identifier>EISSN: 0973-7715</identifier><identifier>DOI: 10.1007/s12088-017-0691-z</identifier><identifier>PMID: 29434400</identifier><language>eng</language><publisher>New Delhi: Springer India</publisher><subject>Bacillus anthracis ; Bacteria ; Biological & chemical terrorism ; Biological & chemical weapons ; Biomedical and Life Sciences ; Bioterrorism ; Cobalt ; Deactivation ; Decontamination ; Expected values ; Fabrics ; Forensic engineering ; Forensic science ; Gamma rays ; Inactivation ; Irradiation ; Life Sciences ; Medical Microbiology ; Microbiology ; Original ; Original Research Article ; Radiation ; Radiation dosage ; Sheep ; Spores ; Standard deviation ; Structural damage ; Viability ; γ Radiation</subject><ispartof>Indian journal of microbiology, 2018-03, Vol.58 (1), p.76-80</ispartof><rights>Association of Microbiologists of India 2017</rights><rights>Indian Journal of Microbiology is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-5e2e19ecf49ad6c4540d439465f8a438265e86e7587cacc4a036c398d183c3033</citedby><cites>FETCH-LOGICAL-c470t-5e2e19ecf49ad6c4540d439465f8a438265e86e7587cacc4a036c398d183c3033</cites><orcidid>0000-0002-7899-6157</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801180/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801180/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,41488,42557,51319,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29434400$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ortatatli, Mesut</creatorcontrib><creatorcontrib>Canitez, Kadir</creatorcontrib><creatorcontrib>Sezigen, Sermet</creatorcontrib><creatorcontrib>Eyison, Ruşen Koray</creatorcontrib><creatorcontrib>Kenar, Levent</creatorcontrib><title>Evaluation of Gamma-Radiation Inactivation of a Bioterrorism Agent, Bacillus anthracis Spores, on Different Materials</title><title>Indian journal of microbiology</title><addtitle>Indian J Microbiol</addtitle><addtitle>Indian J Microbiol</addtitle><description>Decontamination of suspected packages, such as sealed envelopes, liquids and tools that are likely contaminated with biological agents is of great importance. In this study, we aimed to determine the gamma radiation dose required for the decontamination of paper, fabric and liquid materials without causing any damage to the structure of these materials. Each study group included 11 pieces of paper, fabric and sterile saline contaminated with 0.8 × 10
5
virulent
Bacillus anthracis
(B.
anthracis
) spores. These specimens were exposed to doses of 5.49, 11.58, 17.21, 21.75, 27 and 33.1 kilogray (kGy) of gamma radiation from a cobalt-60 source. After irradiation of all the samples, a viability assessment of the B.
anthracis
spores was performed. It was found that full decontamination was achieved with 11.58 kGy on the paper samples and 17.21 kGy on the fabric and liquid samples. It was concluded that a dose of 20 kGy of gamma radiation may be recommended for the inactivation of B.
anthracis
for some surfaces when especially sensitive and valuable materials cannot be wet decontaminated were exposed. In addition, serologic and molecular assays of the suspected packets can be performed for forensic purposes without damaging existing evidence in a bioterror incident.</description><subject>Bacillus anthracis</subject><subject>Bacteria</subject><subject>Biological & chemical terrorism</subject><subject>Biological & chemical weapons</subject><subject>Biomedical and Life Sciences</subject><subject>Bioterrorism</subject><subject>Cobalt</subject><subject>Deactivation</subject><subject>Decontamination</subject><subject>Expected values</subject><subject>Fabrics</subject><subject>Forensic engineering</subject><subject>Forensic science</subject><subject>Gamma rays</subject><subject>Inactivation</subject><subject>Irradiation</subject><subject>Life Sciences</subject><subject>Medical Microbiology</subject><subject>Microbiology</subject><subject>Original</subject><subject>Original Research Article</subject><subject>Radiation</subject><subject>Radiation dosage</subject><subject>Sheep</subject><subject>Spores</subject><subject>Standard deviation</subject><subject>Structural damage</subject><subject>Viability</subject><subject>γ Radiation</subject><issn>0046-8991</issn><issn>0973-7715</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kUtv1TAQhSMEog_4AWyQJTYsGhi_YnuD1BelUhFSC2trcJxbV0l8aydXor8eVylXpVJXY3u-czyjU1XvKHyiAOpzpgy0roGqGhpD67sX1S4YxWulqHxZziCaWhtDd6q9nG8AZGMa-braYUZwIQB2q_l0g_2MU4gjiR05w2HA-hLbsDydj-imsNn2kRyFOPmUYgp5IIcrP04H5Ahd6Ps5Exyn61QumVytY_L5gBTZSeg6nwpIvmORBuzzm-pVV4p_-1D3q19fT38ef6svfpydHx9e1E4omGrpmafGu04YbBsnpIBWcCMa2WkUXLNGet14JbVy6JxA4I3jRrdUc8eB8_3qy-K7nn8PvnVliIS9XacwYPpjIwb7f2cM13YVN1ZqoFRDMfj4YJDi7ezzZIeQne97HH2cs2UA1FDOmCrohyfoTZzTWNaz1BihmC6TF4oulEsx5-S77TAU7H2odgnVllDtfaj2rmjeP95iq_iXYgHYAuTSGlc-Pfr6Wde_SSiuig</recordid><startdate>20180301</startdate><enddate>20180301</enddate><creator>Ortatatli, Mesut</creator><creator>Canitez, Kadir</creator><creator>Sezigen, Sermet</creator><creator>Eyison, Ruşen Koray</creator><creator>Kenar, Levent</creator><general>Springer India</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>04Q</scope><scope>04W</scope><scope>3V.</scope><scope>7T7</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7899-6157</orcidid></search><sort><creationdate>20180301</creationdate><title>Evaluation of Gamma-Radiation Inactivation of a Bioterrorism Agent, Bacillus anthracis Spores, on Different Materials</title><author>Ortatatli, Mesut ; Canitez, Kadir ; Sezigen, Sermet ; Eyison, Ruşen Koray ; Kenar, Levent</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-5e2e19ecf49ad6c4540d439465f8a438265e86e7587cacc4a036c398d183c3033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Bacillus anthracis</topic><topic>Bacteria</topic><topic>Biological & chemical terrorism</topic><topic>Biological & chemical weapons</topic><topic>Biomedical and Life Sciences</topic><topic>Bioterrorism</topic><topic>Cobalt</topic><topic>Deactivation</topic><topic>Decontamination</topic><topic>Expected values</topic><topic>Fabrics</topic><topic>Forensic engineering</topic><topic>Forensic science</topic><topic>Gamma rays</topic><topic>Inactivation</topic><topic>Irradiation</topic><topic>Life Sciences</topic><topic>Medical Microbiology</topic><topic>Microbiology</topic><topic>Original</topic><topic>Original Research Article</topic><topic>Radiation</topic><topic>Radiation dosage</topic><topic>Sheep</topic><topic>Spores</topic><topic>Standard deviation</topic><topic>Structural damage</topic><topic>Viability</topic><topic>γ Radiation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ortatatli, Mesut</creatorcontrib><creatorcontrib>Canitez, Kadir</creatorcontrib><creatorcontrib>Sezigen, Sermet</creatorcontrib><creatorcontrib>Eyison, Ruşen Koray</creatorcontrib><creatorcontrib>Kenar, Levent</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>India Database</collection><collection>India Database: Science & Technology</collection><collection>ProQuest Central (Corporate)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ortatatli, Mesut</au><au>Canitez, Kadir</au><au>Sezigen, Sermet</au><au>Eyison, Ruşen Koray</au><au>Kenar, Levent</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Gamma-Radiation Inactivation of a Bioterrorism Agent, Bacillus anthracis Spores, on Different Materials</atitle><jtitle>Indian journal of microbiology</jtitle><stitle>Indian J Microbiol</stitle><addtitle>Indian J Microbiol</addtitle><date>2018-03-01</date><risdate>2018</risdate><volume>58</volume><issue>1</issue><spage>76</spage><epage>80</epage><pages>76-80</pages><issn>0046-8991</issn><eissn>0973-7715</eissn><abstract>Decontamination of suspected packages, such as sealed envelopes, liquids and tools that are likely contaminated with biological agents is of great importance. In this study, we aimed to determine the gamma radiation dose required for the decontamination of paper, fabric and liquid materials without causing any damage to the structure of these materials. Each study group included 11 pieces of paper, fabric and sterile saline contaminated with 0.8 × 10
5
virulent
Bacillus anthracis
(B.
anthracis
) spores. These specimens were exposed to doses of 5.49, 11.58, 17.21, 21.75, 27 and 33.1 kilogray (kGy) of gamma radiation from a cobalt-60 source. After irradiation of all the samples, a viability assessment of the B.
anthracis
spores was performed. It was found that full decontamination was achieved with 11.58 kGy on the paper samples and 17.21 kGy on the fabric and liquid samples. It was concluded that a dose of 20 kGy of gamma radiation may be recommended for the inactivation of B.
anthracis
for some surfaces when especially sensitive and valuable materials cannot be wet decontaminated were exposed. In addition, serologic and molecular assays of the suspected packets can be performed for forensic purposes without damaging existing evidence in a bioterror incident.</abstract><cop>New Delhi</cop><pub>Springer India</pub><pmid>29434400</pmid><doi>10.1007/s12088-017-0691-z</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-7899-6157</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Springer Online Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Bacillus anthracis Bacteria Biological & chemical terrorism Biological & chemical weapons Biomedical and Life Sciences Bioterrorism Cobalt Deactivation Decontamination Expected values Fabrics Forensic engineering Forensic science Gamma rays Inactivation Irradiation Life Sciences Medical Microbiology Microbiology Original Original Research Article Radiation Radiation dosage Sheep Spores Standard deviation Structural damage Viability γ Radiation |
| title | Evaluation of Gamma-Radiation Inactivation of a Bioterrorism Agent, Bacillus anthracis Spores, on Different Materials |
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