Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

We previously showed that, in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) mouse model of Parkinson's disease (PD), vaccination with bacillus Calmette‐Guerin (BCG) prior to MPTP exposure limited the loss of striatal dopamine (DA) and dopamine transporter (DAT) and prevented the activ...

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Veröffentlicht in:Journal of neuroscience research 2013-10, Vol.91 (10), p.1292-1302
Hauptverfasser: Laćan, Goran, Dang, Hoa, Middleton, Blake, Horwitz, Marcus A., Tian, Jide, Melega, William P., Kaufman, Daniel L.
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Sprache:eng
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