Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update
Recently, the advances in the synthesis of new types of nanomaterials have created several opportunities in drug delivery and targeted therapy applications. Among the various nanostructures, gold nanostructures with controllable physical and chemical properties have received attention for various bi...
Gespeichert in:
| Veröffentlicht in: | 3 Biotech 2018-02, Vol.8 (2), p.113-13, Article 113 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 13 |
|---|---|
| container_issue | 2 |
| container_start_page | 113 |
| container_title | 3 Biotech |
| container_volume | 8 |
| creator | Govindaraju, Saravanan Yun, Kyusik |
| description | Recently, the advances in the synthesis of new types of nanomaterials have created several opportunities in drug delivery and targeted therapy applications. Among the various nanostructures, gold nanostructures with controllable physical and chemical properties have received attention for various biomedical uses, including sensing of biomolecules, in vitro and in vivo bioimaging (as advanced contrast agents for photothermal and bioimaging techniques), photothermolysis of cancer cells, and targeted drug delivery. The attractive properties of gold nanomaterials, particularly, anti-angiogenic properties, are highly useful in a variety of cancers studies. In addition, they can bind many proteins and drugs and can be actively targeted to cancer cells over-expressing cell surface receptors and they are biocompatible in nature with a high atomic number, which directs to greater absorption of kilovoltage X-rays and provides greater contrast than standard agents. In this review, we have summarized the synthesis, structure and functionalization of gold nanostructures, and their biomedical applications with special reference to cancer studies. |
| doi_str_mv | 10.1007/s13205-018-1137-y |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5799112</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2001405236</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-547697c9a730a27c90b2ec24a27bad2ba180a8f20fd0388878ff6936679e397a3</originalsourceid><addsrcrecordid>eNp1kcFLHTEQxkOpVFH_gF5KwEsvq5Nkd5N4EETaKggetFDoIWSz2WdkX7JNdgvvv3fk2YctNJd8ML_5ZoaPkI8MThmAPCtMcGgqYKpiTMhq844ccKahaqRQ73ea_9gnx6U8Ab6GNZrBB7LPdS1AyPqA_LzfxPnRl1BoGugqjT2NNqa1nX0OdizUxp4iEDJ1Njqfq-xHLPa0C2nt--DsSO00jSjmkGI5xw66TD0yR2RvQAt__Pofku9fvzxcXVe3d99uri5vK1dLmKumlq2WTlspwHIU0HHveI26sz3vLFNg1cBh6EEopaQahlaLtpXaCy2tOCQXW99p6XAl5-Oc7WimHNY2b0yywfxdieHRrNJv00itGeNo8PnVIKdfiy-zWYfi_Dja6NNSDAdgNTRctIie_IM-pSVHPM8wrWuuJIBCim0pl1Mp2Q-7ZRiYl_TMNj2D6ZmX9MwGez69vWLX8ScrBPgWKFiKK5_fjP6v6zPklqY2</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1994287008</pqid></control><display><type>article</type><title>Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>SpringerLink Journals - AutoHoldings</source><creator>Govindaraju, Saravanan ; Yun, Kyusik</creator><creatorcontrib>Govindaraju, Saravanan ; Yun, Kyusik</creatorcontrib><description>Recently, the advances in the synthesis of new types of nanomaterials have created several opportunities in drug delivery and targeted therapy applications. Among the various nanostructures, gold nanostructures with controllable physical and chemical properties have received attention for various biomedical uses, including sensing of biomolecules, in vitro and in vivo bioimaging (as advanced contrast agents for photothermal and bioimaging techniques), photothermolysis of cancer cells, and targeted drug delivery. The attractive properties of gold nanomaterials, particularly, anti-angiogenic properties, are highly useful in a variety of cancers studies. In addition, they can bind many proteins and drugs and can be actively targeted to cancer cells over-expressing cell surface receptors and they are biocompatible in nature with a high atomic number, which directs to greater absorption of kilovoltage X-rays and provides greater contrast than standard agents. In this review, we have summarized the synthesis, structure and functionalization of gold nanostructures, and their biomedical applications with special reference to cancer studies.</description><identifier>ISSN: 2190-572X</identifier><identifier>EISSN: 2190-5738</identifier><identifier>DOI: 10.1007/s13205-018-1137-y</identifier><identifier>PMID: 29430374</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Agriculture ; Angiogenesis ; Atomic properties ; Atomic structure ; Biocompatibility ; Bioinformatics ; Biomaterials ; Biomedical materials ; Biomolecules ; Biotechnology ; Cancer ; Cancer Research ; Cell surface ; Chemical properties ; Chemistry ; Chemistry and Materials Science ; Contrast agents ; Drug delivery ; Drug delivery systems ; Gold ; In vivo methods and tests ; Medical imaging ; Nanomaterials ; Nanostructure ; Nanotechnology ; Proteins ; Receptors ; Review ; Review Article ; Stem Cells ; Synthesis</subject><ispartof>3 Biotech, 2018-02, Vol.8 (2), p.113-13, Article 113</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>3 Biotech is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-547697c9a730a27c90b2ec24a27bad2ba180a8f20fd0388878ff6936679e397a3</citedby><cites>FETCH-LOGICAL-c470t-547697c9a730a27c90b2ec24a27bad2ba180a8f20fd0388878ff6936679e397a3</cites><orcidid>0000-0002-6981-8113</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799112/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799112/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27922,27923,41486,42555,51317,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29430374$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Govindaraju, Saravanan</creatorcontrib><creatorcontrib>Yun, Kyusik</creatorcontrib><title>Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update</title><title>3 Biotech</title><addtitle>3 Biotech</addtitle><addtitle>3 Biotech</addtitle><description>Recently, the advances in the synthesis of new types of nanomaterials have created several opportunities in drug delivery and targeted therapy applications. Among the various nanostructures, gold nanostructures with controllable physical and chemical properties have received attention for various biomedical uses, including sensing of biomolecules, in vitro and in vivo bioimaging (as advanced contrast agents for photothermal and bioimaging techniques), photothermolysis of cancer cells, and targeted drug delivery. The attractive properties of gold nanomaterials, particularly, anti-angiogenic properties, are highly useful in a variety of cancers studies. In addition, they can bind many proteins and drugs and can be actively targeted to cancer cells over-expressing cell surface receptors and they are biocompatible in nature with a high atomic number, which directs to greater absorption of kilovoltage X-rays and provides greater contrast than standard agents. In this review, we have summarized the synthesis, structure and functionalization of gold nanostructures, and their biomedical applications with special reference to cancer studies.</description><subject>Agriculture</subject><subject>Angiogenesis</subject><subject>Atomic properties</subject><subject>Atomic structure</subject><subject>Biocompatibility</subject><subject>Bioinformatics</subject><subject>Biomaterials</subject><subject>Biomedical materials</subject><subject>Biomolecules</subject><subject>Biotechnology</subject><subject>Cancer</subject><subject>Cancer Research</subject><subject>Cell surface</subject><subject>Chemical properties</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Contrast agents</subject><subject>Drug delivery</subject><subject>Drug delivery systems</subject><subject>Gold</subject><subject>In vivo methods and tests</subject><subject>Medical imaging</subject><subject>Nanomaterials</subject><subject>Nanostructure</subject><subject>Nanotechnology</subject><subject>Proteins</subject><subject>Receptors</subject><subject>Review</subject><subject>Review Article</subject><subject>Stem Cells</subject><subject>Synthesis</subject><issn>2190-572X</issn><issn>2190-5738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kcFLHTEQxkOpVFH_gF5KwEsvq5Nkd5N4EETaKggetFDoIWSz2WdkX7JNdgvvv3fk2YctNJd8ML_5ZoaPkI8MThmAPCtMcGgqYKpiTMhq844ccKahaqRQ73ea_9gnx6U8Ab6GNZrBB7LPdS1AyPqA_LzfxPnRl1BoGugqjT2NNqa1nX0OdizUxp4iEDJ1Njqfq-xHLPa0C2nt--DsSO00jSjmkGI5xw66TD0yR2RvQAt__Pofku9fvzxcXVe3d99uri5vK1dLmKumlq2WTlspwHIU0HHveI26sz3vLFNg1cBh6EEopaQahlaLtpXaCy2tOCQXW99p6XAl5-Oc7WimHNY2b0yywfxdieHRrNJv00itGeNo8PnVIKdfiy-zWYfi_Dja6NNSDAdgNTRctIie_IM-pSVHPM8wrWuuJIBCim0pl1Mp2Q-7ZRiYl_TMNj2D6ZmX9MwGez69vWLX8ScrBPgWKFiKK5_fjP6v6zPklqY2</recordid><startdate>20180201</startdate><enddate>20180201</enddate><creator>Govindaraju, Saravanan</creator><creator>Yun, Kyusik</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>L6V</scope><scope>LK8</scope><scope>M7P</scope><scope>M7S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6981-8113</orcidid></search><sort><creationdate>20180201</creationdate><title>Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update</title><author>Govindaraju, Saravanan ; Yun, Kyusik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-547697c9a730a27c90b2ec24a27bad2ba180a8f20fd0388878ff6936679e397a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Agriculture</topic><topic>Angiogenesis</topic><topic>Atomic properties</topic><topic>Atomic structure</topic><topic>Biocompatibility</topic><topic>Bioinformatics</topic><topic>Biomaterials</topic><topic>Biomedical materials</topic><topic>Biomolecules</topic><topic>Biotechnology</topic><topic>Cancer</topic><topic>Cancer Research</topic><topic>Cell surface</topic><topic>Chemical properties</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Contrast agents</topic><topic>Drug delivery</topic><topic>Drug delivery systems</topic><topic>Gold</topic><topic>In vivo methods and tests</topic><topic>Medical imaging</topic><topic>Nanomaterials</topic><topic>Nanostructure</topic><topic>Nanotechnology</topic><topic>Proteins</topic><topic>Receptors</topic><topic>Review</topic><topic>Review Article</topic><topic>Stem Cells</topic><topic>Synthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Govindaraju, Saravanan</creatorcontrib><creatorcontrib>Yun, Kyusik</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>3 Biotech</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Govindaraju, Saravanan</au><au>Yun, Kyusik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update</atitle><jtitle>3 Biotech</jtitle><stitle>3 Biotech</stitle><addtitle>3 Biotech</addtitle><date>2018-02-01</date><risdate>2018</risdate><volume>8</volume><issue>2</issue><spage>113</spage><epage>13</epage><pages>113-13</pages><artnum>113</artnum><issn>2190-572X</issn><eissn>2190-5738</eissn><abstract>Recently, the advances in the synthesis of new types of nanomaterials have created several opportunities in drug delivery and targeted therapy applications. Among the various nanostructures, gold nanostructures with controllable physical and chemical properties have received attention for various biomedical uses, including sensing of biomolecules, in vitro and in vivo bioimaging (as advanced contrast agents for photothermal and bioimaging techniques), photothermolysis of cancer cells, and targeted drug delivery. The attractive properties of gold nanomaterials, particularly, anti-angiogenic properties, are highly useful in a variety of cancers studies. In addition, they can bind many proteins and drugs and can be actively targeted to cancer cells over-expressing cell surface receptors and they are biocompatible in nature with a high atomic number, which directs to greater absorption of kilovoltage X-rays and provides greater contrast than standard agents. In this review, we have summarized the synthesis, structure and functionalization of gold nanostructures, and their biomedical applications with special reference to cancer studies.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29430374</pmid><doi>10.1007/s13205-018-1137-y</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-6981-8113</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2190-572X |
| ispartof | 3 Biotech, 2018-02, Vol.8 (2), p.113-13, Article 113 |
| issn | 2190-572X 2190-5738 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5799112 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; SpringerLink Journals - AutoHoldings |
| subjects | Agriculture Angiogenesis Atomic properties Atomic structure Biocompatibility Bioinformatics Biomaterials Biomedical materials Biomolecules Biotechnology Cancer Cancer Research Cell surface Chemical properties Chemistry Chemistry and Materials Science Contrast agents Drug delivery Drug delivery systems Gold In vivo methods and tests Medical imaging Nanomaterials Nanostructure Nanotechnology Proteins Receptors Review Review Article Stem Cells Synthesis |
| title | Synthesis of gold nanomaterials and their cancer-related biomedical applications: an update |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T19%3A20%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis%20of%20gold%20nanomaterials%20and%20their%20cancer-related%20biomedical%20applications:%20an%20update&rft.jtitle=3%20Biotech&rft.au=Govindaraju,%20Saravanan&rft.date=2018-02-01&rft.volume=8&rft.issue=2&rft.spage=113&rft.epage=13&rft.pages=113-13&rft.artnum=113&rft.issn=2190-572X&rft.eissn=2190-5738&rft_id=info:doi/10.1007/s13205-018-1137-y&rft_dat=%3Cproquest_pubme%3E2001405236%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1994287008&rft_id=info:pmid/29430374&rfr_iscdi=true |