Broad impact of extracellular DNA on biofilm formation by clinically isolated Methicillin-resistant and -sensitive strains of Staphylococcus aureus

Staphylococcus aureus is a major causative agent for biofilm-associated infections. Inside biofilms, S . aureus cells are embedded in an extracellular matrix (ECM) composed of polysaccharide-intercellular adhesins (PIA), proteins, and/or extracellular DNA (eDNA). However, the importance of each comp...

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Veröffentlicht in:	Scientific reports 2018-02, Vol.8 (1), p.2254-11, Article 2254
Hauptverfasser:	Sugimoto, Shinya, Sato, Fumiya, Miyakawa, Reina, Chiba, Akio, Onodera, Shoichi, Hori, Seiji, Mizunoe, Yoshimitsu
Format:	Artikel
Sprache:	eng
Schlagworte:	14/34 38/71 45/70 631/1647/2234 631/326/2565/107 631/326/421 631/326/46 631/45/147 82/29 Adhesins Bacteriological Techniques Biofilms Biofilms - growth & development Cell culture Clinical isolates Deoxyribonuclease Deoxyribonuclease I - metabolism Deoxyribonucleic acid DNA DNA, Bacterial - metabolism Drug resistance Endopeptidase K Endopeptidase K - metabolism Environmental DNA Extracellular matrix Gram-positive bacteria Humanities and Social Sciences Humans Methicillin Methicillin Resistance multidisciplinary Pathogens Proteinase Science Science (multidisciplinary) Sodium chloride Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - growth & development Staphylococcus aureus - isolation & purification Staphylococcus aureus - metabolism Supplements
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