Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo ; therapeutic and chemopreventive applications

DNA hypomethylation coordinately targets various signaling pathways involved in tumor growth and metastasis. At present, there are no approved therapeutic modalities that target hypomethylation. In this regard, we examined the therapeutic plausibility of using universal methyl group donor S-adenosyl...

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Veröffentlicht in:	Oncotarget 2018-01, Vol.9 (4), p.5169-5183
Hauptverfasser:	Mahmood, Niaz, Cheishvili, David, Arakelian, Ani, Tanvir, Imrana, Khan, Haseeb Ahmed, Pépin, Anne-Sophie, Szyf, Moshe, Rabbani, Shafaat A
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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