Enantiomeric Recognition of d- and l‑Lactate by CEST with the Aid of a Paramagnetic Shift Reagent

A previous report demonstrated that EuDO3A could be used as an NMR shift reagent for imaging extracellular lactate produced by cancer cells using CEST imaging. In this work, a series of heptadentate macrocyclic YbDO3A-trisamide complexes with δ-chiral carbons in the three pendant side-arms were exam...

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Veröffentlicht in:	Journal of the American Chemical Society 2017-12, Vol.139 (48), p.17431-17437
Hauptverfasser:	Zhang, Lei, Martins, André F, Zhao, Piyu, Tieu, Michael, Esteban-Gómez, David, McCandless, Gregory T, Platas-Iglesias, Carlos, Sherry, A. Dean
Format:	Artikel
Sprache:	eng
Schlagworte:	Indicators and Reagents Lactic Acid - analysis Lactic Acid - chemistry Lanthanoid Series Elements - chemistry Magnetic Resonance Spectroscopy - methods
Online-Zugang:	Volltext
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