In vitro study on the role of SOX9 in trastuzumab resistance of adenocarcinoma of the esophagogastric junction

Trastuzumab is recommended for the treatment of human epidermal growth factor receptor 2-positive adenocarcinoma of the esophagogastric junction (AEG) in combination with chemotherapy; however, drug resistance has severely affected its clinical application. The present study aimed to investigate the...

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Veröffentlicht in:	Experimental and therapeutic medicine 2018-03, Vol.15 (3), p.3103-3107
Hauptverfasser:	Hong, Yingcai, Chen, Huaisheng, Rao, Zhanpeng, Peng, Bin, Hu, Hong, Lin, Shaolin, Xu, Zhenglei
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer therapies Cell cycle Cell growth Chemotherapy Dosage and administration Drug resistance Drug therapy Esophageal cancer Gastric cancer Immunotherapy Kinases Medical prognosis Monoclonal antibodies Observations Phosphorylation Polyclonal antibodies Proteins Stomach cancer Targeted cancer therapy Trastuzumab
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