B1a B cells require autophagy for metabolic homeostasis and self-renewal

Specific metabolic programs are activated by immune cells to fulfill their functional roles, which include adaptations to their microenvironment. B1 B cells are tissue-resident, innate-like B cells. They have many distinct properties, such as the capacity to self-renew and the ability to rapidly res...

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Veröffentlicht in:The Journal of experimental medicine 2018-02, Vol.215 (2), p.399-413
Hauptverfasser: Clarke, Alexander J, Riffelmacher, Thomas, Braas, Daniel, Cornall, Richard J, Simon, Anna Katharina
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Sprache:eng
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