Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence

is a versatile bacterial pathogen that can cause significant disease burden and mortality. Like other pathogens, must adapt to its environment to produce virulence factors to survive the immune responses evoked by infection. Despite the importance of environmental signals for pathogenicity, only a l...

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Veröffentlicht in:	mBio 2018-01, Vol.9 (1)
Hauptverfasser:	Harper, Lamia, Balasubramanian, Divya, Ohneck, Elizabeth A, Sause, William E, Chapman, Jessica, Mejia-Sosa, Bryan, Lhakhang, Tenzin, Heguy, Adriana, Tsirigos, Aristotelis, Ueberheide, Beatrix, Boyd, Jeffrey M, Lun, Desmond S, Torres, Victor J
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Regulation, Bacterial - drug effects Humans Metabolism - drug effects Methicillin-Resistant Staphylococcus aureus - metabolism Methicillin-Resistant Staphylococcus aureus - pathogenicity Pyruvic Acid - metabolism Staphylococcal Infections Virulence Virulence Factors - biosynthesis
Online-Zugang:	Volltext
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