Alanine scanning mutagenesis of SP70 epitope in characterizing species‑specific antibodies induced by enterovirus 71‑based antigens

The enterovirus 71 (EV71) SP70 epitope, derived from amino acids 208‑222 of VP1, is a neutralizing epitope. The present study aimed to assess the inter‑species differences of the antibodies induced by EV71‑based antigens in responses to SP70 mutant peptides. BALB/c mice and Lou/C rats were immunized...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular medicine reports 2018-01, Vol.17 (1), p.1006-1014
Hauptverfasser:	Gao, Meng, Zhang, Feng, Zhu, Yun, Gao, Limei, Jiang, Yunshui, Luo, Yongneng, Zhuang, Fangchang, Mao, Zian, Mao, Jiangsen
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Alanine Antigen-antibody reactions Antigens Cloning Enzyme-linked immunosorbent assay Epidemics Epitopes Immune response Immunofluorescence Laboratory animals Medical research Monoclonal antibodies Multiple myeloma Mutagenesis Mutation Observations Peptides Polyclonal antibodies Properties Proteins Scanning mutagenesis Species
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!