Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway

The present study aimed to investigate the role of relaxin (RLX) on high glucose (HG)-induced cardiomyocyte hypertrophy and apoptosis, as well as the possible molecular mechanism. H9c2 cells were exposed to 33 mmol/l HG with or without RLX (100 nmol/ml). Cell viability, apoptosis, oxidative stress,...

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Veröffentlicht in:	Experimental and therapeutic medicine 2018-01, Vol.15 (1), p.691-698
Hauptverfasser:	Wei, Xiao, Yang, Yuan, Jiang, Yin-Jiu, Lei, Jian-Ming, Guo, Jing-Wen, Xiao, Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Heart hypertrophy Natriuretic peptides Risk factors
Online-Zugang:	Volltext
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