Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer

A distinction between indolent and aggressive disease is a major challenge in diagnostics of prostate cancer. As genetic heterogeneity and complexity may influence clinical outcome, we have initiated studies on single tumor cell genomics. In this study, we demonstrate that sparse DNA sequencing of s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2018-01, Vol.78 (2), p.348-358
Hauptverfasser:	Alexander, Joan, Kendall, Jude, McIndoo, Jean, Rodgers, Linda, Aboukhalil, Robert, Levy, Dan, Stepansky, Asya, Sun, Guoli, Chobardjiev, Lubomir, Riggs, Michael, Cox, Hilary, Hakker, Inessa, Nowak, Dawid G, Laze, Juliana, Llukani, Elton, Srivastava, Abhishek, Gruschow, Siobhan, Yadav, Shalini S, Robinson, Brian, Atwal, Gurinder, Trotman, Lloyd C, Lepor, Herbert, Hicks, James, Wigler, Michael, Krasnitz, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Aged Aged, 80 and over Biomarkers, Tumor - genetics Biopsy Cores Diagnosis DNA sequencing Genomic analysis Genomics Genomics - methods Histopathology Humans Male Malignancy Middle Aged Neoplasia Neoplasm Grading Neoplasm Staging Nuclei Nuclei (cytology) Phylogeny Prognosis Prostate Prostate cancer Prostatectomy Prostatic Neoplasms - diagnosis Prostatic Neoplasms - genetics Prostatic Neoplasms - surgery Risk Assessment Single-Cell Analysis - methods Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!