NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease

Of interest to the etiology of demyelinating autoimmune disease is the potential to aberrantly activate CD4 T cells due to cross-recognition of multiple self-epitopes such as has been suggested for myelin oligodendrocyte glycoprotein epitope 35-55 (MOG ) and neurofilament medium protein epitope 15-3...

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