Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells

The dorsal root ganglia (DRG) consist of a multitude of sensory neuronal subtypes that function to relay sensory stimuli, including temperature, pressure, pain and position to the central nervous system. Our knowledge of DRG sensory neurons have been predominantly driven by animal studies and consid...

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Veröffentlicht in:	Scientific reports 2018-01, Vol.8 (1), p.603-12, Article 603
Hauptverfasser:	Alshawaf, Abdullah Jawad, Viventi, Serena, Qiu, Wanzhi, D’Abaco, Giovanna, Nayagam, Bryony, Erlichster, Michael, Chana, Gursharan, Everall, Ian, Ivanusic, Jason, Skafidas, Efstratios, Dottori, Mirella
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/106 14/19 38 38/77 631/136/142 631/378/1959/2605 631/378/3917 631/532/1360 82/51 9/30 Biomarkers - metabolism Cell culture Cell Culture Techniques - methods Cell Differentiation Cell Line Central nervous system Dorsal root ganglia Embryo cells Gene expression Human Embryonic Stem Cells - cytology Human Embryonic Stem Cells - metabolism Humanities and Social Sciences Humans Microelectrodes multidisciplinary Neural crest Pain Peripheral Nervous System - cytology Phenotype Science Science (multidisciplinary) Sensory neurons Sensory Receptor Cells - cytology Sensory Receptor Cells - metabolism Sensory stimuli Stem cell transplantation Stem cells
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