Directing Biosynthesis: Practical Supply of Natural and Unnatural Cyanobactins

The increasingly rapid accumulation of genomic information is revolutionizing natural products discovery. However, the translation of sequence data to chemical products remains a challenge. Here, we detail methods used to circumvent the supply problem of cyanobactin natural products, both by enginee...

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Veröffentlicht in:	Methods in enzymology 2016, Vol.575, p.1-20
Hauptverfasser:	Sardar, D, Tianero, M D, Schmidt, E W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Biological Products - chemistry Biological Products - metabolism Biosynthetic Pathways Cyanobacteria - chemistry Cyanobacteria - genetics Cyanobacteria - metabolism Escherichia coli - genetics Escherichia coli - metabolism Genes, Bacterial Metabolic Engineering - methods Multigene Family Peptides, Cyclic - chemistry Peptides, Cyclic - genetics Peptides, Cyclic - metabolism Protein Processing, Post-Translational Ribosomes - genetics Ribosomes - metabolism
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