Precision oncology for acute myeloid leukemia using a knowledge bank approach

Peter Campbell, Hartmut Döhner and colleagues present an analysis of genetic mutations and clinical information from 1,540 patients with acute myeloid leukemia, demonstrating the utility of clinical knowledge banks for personalized medicine. They show that use of their approach could reduce the numb...

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Veröffentlicht in:	Nature genetics 2017-03, Vol.49 (3), p.332-340
Hauptverfasser:	Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott, Ultan, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/212/2166 631/67/1990/283/1897 692/308/2056 Accuracy Acute myelocytic leukemia Adolescent Adult Aged Aged, 80 and over Agriculture analysis Animal Genetics and Genomics Biomedicine Cancer Cancer Research Cancer therapies Care and treatment Chemotherapy Clinical outcomes Clinical trials Clinical Trials as Topic Decision Making Development and progression Female Gene Function Gene mutation Genetic aspects Genomes Genomics Health aspects Heterogeneity Human Genetics Humans Innovations Knowledge Leukemia Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - mortality Male Medical prognosis Medicine Middle Aged Multicenter Studies as Topic Mutation Patients Precision medicine Precision Medicine - methods Randomized Controlled Trials as Topic Statistical models Studies Survival Survival Rate Transplants & implants Young Adult
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