Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway

Fat infiltration within the bone marrow is easily observed in some postmenopausal women. Those fats are mainly derived from bone marrow mesenchymal stem cells (BMMSCs). The increment of adipocytes derived from BMMSCs leads to decreased osteoblasts derived from BMMSCs, so the bidirectional differenti...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2017-01, Vol.2017 (2017), p.1-12
Hauptverfasser:	Guo, Jin-feng, Yao, Xu-dong, Guo, Jia-chao, Jing, Xing-zhi, Xiang, Wei, Bao, Yuan, Huang, Jun-ming, Wang, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipogenesis Bone density Bone marrow Bone mass Bones Cancellous bone Computed tomography Density Ethylenediaminetetraacetic acid Fats Femur Gene expression Immunofluorescence Kinases Menopause Mesenchymal stem cells Mesenchyme Mice Mutation Osteoblastogenesis Osteoblasts Osteogenesis Osteoporosis Ovariectomy Post-menopause Postmenopausal women Rodents Signal transduction Staining Stem cell transplantation Stem cells Traditional Chinese medicine Wnt protein
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