Alpha-1-antitrypsin functions as a protective factor in preeclampsia through activating Smad2 and inhibitor of DNA binding 4

Pre-eclampsia (PE) is one of the most common reason for high morbidity and mortality of maternal and prenatal infants. Production from oxidative stress results in maternal ROS system and anti-oxidation defense system imbalance to promote tissue ischemia and hypoxia, and ultimately impairs the matern...

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Veröffentlicht in:Oncotarget 2017-12, Vol.8 (68), p.113002-113012
Hauptverfasser: Feng, Yaling, Wang, Nan, Xu, Jianjuan, Zou, Jinfang, Liang, Xi, Liu, Huan, Chen, Ying
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Sprache:eng
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