Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts

The invasion of activated fibroblasts is a key mechanism of tissue fibrosis pathology. The recognition and uptake of apoptotic cells can induce the anti-fibrogenic programming of macrophages. We demonstrate that after interacting with apoptotic cells, macrophages secrete bioactive molecules that ant...

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Veröffentlicht in:	Oncotarget 2017-12, Vol.8 (68), p.112297-112312
Hauptverfasser:	Kim, Yong-Bae, Yoon, Young-So, Choi, Youn-Hee, Park, Eun-Mi, Kang, Jihee Lee
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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