Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance

Schizophrenia is a serious mental illness, involving disruptions in thought and behavior, with a worldwide prevalence of about one percent. Although highly heritable, much of the genetic liability of schizophrenia is yet to be explained. We searched for susceptibility loci in multiplex, multigenerat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of medical genetics. Part B, Neuropsychiatric genetics Neuropsychiatric genetics, 2017-12, Vol.174 (8), p.817-827
Hauptverfasser:	Kos, Mark Z., Carless, Melanie A., Peralta, Juan, Curran, Joanne E., Quillen, Ellen E., Almeida, Marcio, Blackburn, August, Blondell, Lucy, Roalf, David R., Pogue‐Geile, Michael F., Gur, Ruben C., Göring, Harald H.H., Nimgaonkar, Vishwajit L., Gur, Raquel E., Almasy, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Axonogenesis Case-Control Studies Cognition Epistasis Exome exome sequences Family Female Gene expression Genetic Markers Genetic Predisposition to Disease Genetics Genome-Wide Association Study Humans Kinases Learning Male Memory Mental disorders Mental Status and Dementia Tests Middle Aged Neural cell adhesion molecule Neurocognitive Disorders - diagnosis Neurocognitive Disorders - epidemiology Neurocognitive Disorders - genetics Polymorphism, Single Nucleotide Protein interaction Proteins Risk Factors Schizophrenia Schizophrenia - complications Schizophrenia - genetics Single-nucleotide polymorphism Synaptic plasticity Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!