IR-780-loaded polymeric micelles enhance the efficacy of photothermal therapy in treating breast cancer lymphatic metastasis in mice

Cancer metastasis is responsible for over 90% of breast cancer-related deaths, and inhibiting lymph node metastasis is an option to treat metastatic disease. Herein, we report the use of IR-780-Ioaded polymeric micelles （IPMs） for effective photothermal therapy （PTT） of breast cancer lymphatic metas...

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Veröffentlicht in:	Acta pharmacologica Sinica 2018-01, Vol.39 (1), p.132-139
Hauptverfasser:	He, Bin, Hu, Hai-yan, Tan, Tao, Wang, Hong, Sun, Kao-xiang, Li, Ya-ping, Zhang, Zhi-wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Animals Antineoplastic Agents - radiation effects Antineoplastic Agents - therapeutic use Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - pathology Cell Line, Tumor Drug Carriers - chemistry Drug Carriers - radiation effects Drug Carriers - therapeutic use Female Heating Immunology Indoles - radiation effects Indoles - therapeutic use Internal Medicine Intravenous administration Irradiation Laser Therapy - methods Lasers Lymph nodes Lymphatic Metastasis - prevention & control Medical Microbiology Metastases Metastasis Mice, Nude Micelles Original original-article Particle Size Pharmacology/Toxicology Phosphatidylethanolamines - chemistry Phosphatidylethanolamines - radiation effects Phosphatidylethanolamines - therapeutic use Phototherapy - methods Polyethylene Glycols - chemistry Polyethylene Glycols - radiation effects Polyethylene Glycols - therapeutic use Vaccine
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