Mixed guanine, adenine base quartets: possible roles of protons and metal ions in their stabilization

Structural variations of the well-known guanine quartet (G 4 ) motif in nucleic acid structures, namely substitution of two guanine bases (G) by two adenine (A) nucleobases in mutual trans positions, are discussed and studied by density functional theory (DFT) methods. This work was initiated by thr...

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Veröffentlicht in:	Journal of biological inorganic chemistry 2018-01, Vol.23 (1), p.41-49
Hauptverfasser:	Megger, Dominik A., Lax, Patrick M., Paauwe, Jeroen, Fonseca Guerra, Célia, Lippert, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Bases (nucleic acids) Biochemistry Biomedical and Life Sciences Deoxyribonucleic acid DNA Guanine Inorganic chemistry Ions Life Sciences Microbiology Original Paper Protons Special issue to celebrate the 80th birthday of Helmut Sigel
Online-Zugang:	Volltext
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