Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status
Purpose Heat adaptation (HA) is critical to performance and health in a hot environment. Transition from short-term heat acclimatisation (STHA) to long-term heat acclimatisation (LTHA) is characterised by decreased autonomic disturbance and increased protection from thermal injury. A standard heat t...
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| Veröffentlicht in: | European journal of applied physiology 2018-01, Vol.118 (1), p.165-174 |
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| creator | Stacey, Major Michael John Delves, S. K. Woods, D. R. Britland, S. E. Macconnachie, L. Allsopp, A. J. Brett, S. J. Fallowfield, J. L. Boos, C. J. |
| description | Purpose
Heat adaptation (HA) is critical to performance and health in a hot environment. Transition from short-term heat acclimatisation (STHA) to long-term heat acclimatisation (LTHA) is characterised by decreased autonomic disturbance and increased protection from thermal injury. A standard heat tolerance test (HTT) is recommended for validating exercise performance status, but any role in distinguishing STHA from LTHA is unreported. The aims of this study were to (1) define performance status by serial HTT during structured natural HA, (2) evaluate surrogate markers of autonomic activation, including heart rate variability (HRV), in relation to HA status.
Methods
Participants (
n
= 13) were assessed by HTT (60-min block-stepping, 50%
V
O
2
peak) during STHA (Day 2, 6 and 9) and LTHA (Day 23). Core temperature (Tc) and heart rate (HR) were measured every 5 min. Sampling for HRV indices (RMSSD, LF:HF) and sympathoadrenal blood measures (cortisol, nephrines) was undertaken before and after (POST) each HTT.
Results
Significant (
P
|
| doi_str_mv | 10.1007/s00421-017-3758-y |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5754393</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1963269981</sourcerecordid><originalsourceid>FETCH-LOGICAL-c518t-e5d98453df2d8b0ee7fef9558baf4b89b1eada1e2be87dbc76e74156aefd11da3</originalsourceid><addsrcrecordid>eNp1kU1r3DAQhkVpaNK0P6CXIuilFzca27KkS6GEtCkEekluBTG2xlkFr7yV5IX991VwuqSFniRmnnnn42XsHYhPIIS6SEK0NVQCVNUoqavDC3YGbWOqrqnVy-MfzCl7ndKDEELXoF-x09pAraQwZ-znNWHMPGImvsfosfeTzweOwfHdhGmLPNBuE32gxH3geUOc9jgtmP0c-DzyDWHmOAyT35ZYWuMpY17SG3Yy4pTo7dN7zu6-Xt1eXlc3P759v_xyUw0SdK5IOqNb2bixdroXRGqk0UipexzbXpseCB0C1T1p5fpBdaRakB3S6AAcNufs86q7W_otuYFCjjjZXSwjxYOd0du_M8Fv7P28t1LJcqKmCHx8Eojzr4VStlufBpomDDQvyYIpF-2M0VDQD_-gD_MSQ1mvULrtlNFaFApWaohzSpHG4zAg7KN3dvXOFu_so3f2UGreP9_iWPHHrALUK5BKKtxTfNb6v6q_AUYZqIw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1984679880</pqid></control><display><type>article</type><title>Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Stacey, Major Michael John ; Delves, S. K. ; Woods, D. R. ; Britland, S. E. ; Macconnachie, L. ; Allsopp, A. J. ; Brett, S. J. ; Fallowfield, J. L. ; Boos, C. J.</creator><creatorcontrib>Stacey, Major Michael John ; Delves, S. K. ; Woods, D. R. ; Britland, S. E. ; Macconnachie, L. ; Allsopp, A. J. ; Brett, S. J. ; Fallowfield, J. L. ; Boos, C. J.</creatorcontrib><description>Purpose
Heat adaptation (HA) is critical to performance and health in a hot environment. Transition from short-term heat acclimatisation (STHA) to long-term heat acclimatisation (LTHA) is characterised by decreased autonomic disturbance and increased protection from thermal injury. A standard heat tolerance test (HTT) is recommended for validating exercise performance status, but any role in distinguishing STHA from LTHA is unreported. The aims of this study were to (1) define performance status by serial HTT during structured natural HA, (2) evaluate surrogate markers of autonomic activation, including heart rate variability (HRV), in relation to HA status.
Methods
Participants (
n
= 13) were assessed by HTT (60-min block-stepping, 50%
V
O
2
peak) during STHA (Day 2, 6 and 9) and LTHA (Day 23). Core temperature (Tc) and heart rate (HR) were measured every 5 min. Sampling for HRV indices (RMSSD, LF:HF) and sympathoadrenal blood measures (cortisol, nephrines) was undertaken before and after (POST) each HTT.
Results
Significant (
P
< 0.05) interactions existed for Tc, logLF:HF, cortisol and nephrines (two-way ANOVA; HTT by Day). Relative to LTHA, POST results differed significantly for Tc (Day 2, 6 and 9), HR (Day 2), logRMSSD (Day 2 and Day 6), logLF:HF (Day 2 and Day 6), cortisol (Day 2) and nephrines (Day 2 and Day 9). POST differences in HRV (Day 6 vs. 23) were + 9.9% (logRMSSD) and − 18.6% (logLF:HF).
Conclusions
Early reductions in HR and cortisol characterised STHA, whereas LTHA showed diminished excitability by Tc, HRV and nephrine measures. Measurement of HRV may have potential to aid real-time assessment of readiness for activity in the heat.</description><identifier>ISSN: 1439-6319</identifier><identifier>EISSN: 1439-6327</identifier><identifier>DOI: 10.1007/s00421-017-3758-y</identifier><identifier>PMID: 29127509</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acclimatization ; Adrenal glands ; Adult ; Autonomic Nervous System - physiology ; Biomedical and Life Sciences ; Biomedicine ; Cortisol ; Excitability ; Exercise Tolerance ; Heart Rate ; Heat tolerance ; Hormones ; Hot Temperature ; Human Physiology ; Humans ; Hydrocortisone - blood ; Male ; Membrane Proteins - blood ; Military Personnel ; Occupational Medicine/Industrial Medicine ; Original ; Original Article ; Sports Medicine ; Sympathetic nervous system ; Thermal injury</subject><ispartof>European journal of applied physiology, 2018-01, Vol.118 (1), p.165-174</ispartof><rights>The Author(s) 2017</rights><rights>European Journal of Applied Physiology is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c518t-e5d98453df2d8b0ee7fef9558baf4b89b1eada1e2be87dbc76e74156aefd11da3</citedby><cites>FETCH-LOGICAL-c518t-e5d98453df2d8b0ee7fef9558baf4b89b1eada1e2be87dbc76e74156aefd11da3</cites><orcidid>0000-0002-5086-9025</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00421-017-3758-y$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00421-017-3758-y$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29127509$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stacey, Major Michael John</creatorcontrib><creatorcontrib>Delves, S. K.</creatorcontrib><creatorcontrib>Woods, D. R.</creatorcontrib><creatorcontrib>Britland, S. E.</creatorcontrib><creatorcontrib>Macconnachie, L.</creatorcontrib><creatorcontrib>Allsopp, A. J.</creatorcontrib><creatorcontrib>Brett, S. J.</creatorcontrib><creatorcontrib>Fallowfield, J. L.</creatorcontrib><creatorcontrib>Boos, C. J.</creatorcontrib><title>Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status</title><title>European journal of applied physiology</title><addtitle>Eur J Appl Physiol</addtitle><addtitle>Eur J Appl Physiol</addtitle><description>Purpose
Heat adaptation (HA) is critical to performance and health in a hot environment. Transition from short-term heat acclimatisation (STHA) to long-term heat acclimatisation (LTHA) is characterised by decreased autonomic disturbance and increased protection from thermal injury. A standard heat tolerance test (HTT) is recommended for validating exercise performance status, but any role in distinguishing STHA from LTHA is unreported. The aims of this study were to (1) define performance status by serial HTT during structured natural HA, (2) evaluate surrogate markers of autonomic activation, including heart rate variability (HRV), in relation to HA status.
Methods
Participants (
n
= 13) were assessed by HTT (60-min block-stepping, 50%
V
O
2
peak) during STHA (Day 2, 6 and 9) and LTHA (Day 23). Core temperature (Tc) and heart rate (HR) were measured every 5 min. Sampling for HRV indices (RMSSD, LF:HF) and sympathoadrenal blood measures (cortisol, nephrines) was undertaken before and after (POST) each HTT.
Results
Significant (
P
< 0.05) interactions existed for Tc, logLF:HF, cortisol and nephrines (two-way ANOVA; HTT by Day). Relative to LTHA, POST results differed significantly for Tc (Day 2, 6 and 9), HR (Day 2), logRMSSD (Day 2 and Day 6), logLF:HF (Day 2 and Day 6), cortisol (Day 2) and nephrines (Day 2 and Day 9). POST differences in HRV (Day 6 vs. 23) were + 9.9% (logRMSSD) and − 18.6% (logLF:HF).
Conclusions
Early reductions in HR and cortisol characterised STHA, whereas LTHA showed diminished excitability by Tc, HRV and nephrine measures. Measurement of HRV may have potential to aid real-time assessment of readiness for activity in the heat.</description><subject>Acclimatization</subject><subject>Adrenal glands</subject><subject>Adult</subject><subject>Autonomic Nervous System - physiology</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cortisol</subject><subject>Excitability</subject><subject>Exercise Tolerance</subject><subject>Heart Rate</subject><subject>Heat tolerance</subject><subject>Hormones</subject><subject>Hot Temperature</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>Male</subject><subject>Membrane Proteins - blood</subject><subject>Military Personnel</subject><subject>Occupational Medicine/Industrial Medicine</subject><subject>Original</subject><subject>Original Article</subject><subject>Sports Medicine</subject><subject>Sympathetic nervous system</subject><subject>Thermal injury</subject><issn>1439-6319</issn><issn>1439-6327</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU1r3DAQhkVpaNK0P6CXIuilFzca27KkS6GEtCkEekluBTG2xlkFr7yV5IX991VwuqSFniRmnnnn42XsHYhPIIS6SEK0NVQCVNUoqavDC3YGbWOqrqnVy-MfzCl7ndKDEELXoF-x09pAraQwZ-znNWHMPGImvsfosfeTzweOwfHdhGmLPNBuE32gxH3geUOc9jgtmP0c-DzyDWHmOAyT35ZYWuMpY17SG3Yy4pTo7dN7zu6-Xt1eXlc3P759v_xyUw0SdK5IOqNb2bixdroXRGqk0UipexzbXpseCB0C1T1p5fpBdaRakB3S6AAcNufs86q7W_otuYFCjjjZXSwjxYOd0du_M8Fv7P28t1LJcqKmCHx8Eojzr4VStlufBpomDDQvyYIpF-2M0VDQD_-gD_MSQ1mvULrtlNFaFApWaohzSpHG4zAg7KN3dvXOFu_so3f2UGreP9_iWPHHrALUK5BKKtxTfNb6v6q_AUYZqIw</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Stacey, Major Michael John</creator><creator>Delves, S. K.</creator><creator>Woods, D. R.</creator><creator>Britland, S. E.</creator><creator>Macconnachie, L.</creator><creator>Allsopp, A. J.</creator><creator>Brett, S. J.</creator><creator>Fallowfield, J. L.</creator><creator>Boos, C. J.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5086-9025</orcidid></search><sort><creationdate>20180101</creationdate><title>Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status</title><author>Stacey, Major Michael John ; Delves, S. K. ; Woods, D. R. ; Britland, S. E. ; Macconnachie, L. ; Allsopp, A. J. ; Brett, S. J. ; Fallowfield, J. L. ; Boos, C. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c518t-e5d98453df2d8b0ee7fef9558baf4b89b1eada1e2be87dbc76e74156aefd11da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Acclimatization</topic><topic>Adrenal glands</topic><topic>Adult</topic><topic>Autonomic Nervous System - physiology</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cortisol</topic><topic>Excitability</topic><topic>Exercise Tolerance</topic><topic>Heart Rate</topic><topic>Heat tolerance</topic><topic>Hormones</topic><topic>Hot Temperature</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>Male</topic><topic>Membrane Proteins - blood</topic><topic>Military Personnel</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Original</topic><topic>Original Article</topic><topic>Sports Medicine</topic><topic>Sympathetic nervous system</topic><topic>Thermal injury</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stacey, Major Michael John</creatorcontrib><creatorcontrib>Delves, S. K.</creatorcontrib><creatorcontrib>Woods, D. R.</creatorcontrib><creatorcontrib>Britland, S. E.</creatorcontrib><creatorcontrib>Macconnachie, L.</creatorcontrib><creatorcontrib>Allsopp, A. J.</creatorcontrib><creatorcontrib>Brett, S. J.</creatorcontrib><creatorcontrib>Fallowfield, J. L.</creatorcontrib><creatorcontrib>Boos, C. J.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European journal of applied physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stacey, Major Michael John</au><au>Delves, S. K.</au><au>Woods, D. R.</au><au>Britland, S. E.</au><au>Macconnachie, L.</au><au>Allsopp, A. J.</au><au>Brett, S. J.</au><au>Fallowfield, J. L.</au><au>Boos, C. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status</atitle><jtitle>European journal of applied physiology</jtitle><stitle>Eur J Appl Physiol</stitle><addtitle>Eur J Appl Physiol</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>118</volume><issue>1</issue><spage>165</spage><epage>174</epage><pages>165-174</pages><issn>1439-6319</issn><eissn>1439-6327</eissn><abstract>Purpose
Heat adaptation (HA) is critical to performance and health in a hot environment. Transition from short-term heat acclimatisation (STHA) to long-term heat acclimatisation (LTHA) is characterised by decreased autonomic disturbance and increased protection from thermal injury. A standard heat tolerance test (HTT) is recommended for validating exercise performance status, but any role in distinguishing STHA from LTHA is unreported. The aims of this study were to (1) define performance status by serial HTT during structured natural HA, (2) evaluate surrogate markers of autonomic activation, including heart rate variability (HRV), in relation to HA status.
Methods
Participants (
n
= 13) were assessed by HTT (60-min block-stepping, 50%
V
O
2
peak) during STHA (Day 2, 6 and 9) and LTHA (Day 23). Core temperature (Tc) and heart rate (HR) were measured every 5 min. Sampling for HRV indices (RMSSD, LF:HF) and sympathoadrenal blood measures (cortisol, nephrines) was undertaken before and after (POST) each HTT.
Results
Significant (
P
< 0.05) interactions existed for Tc, logLF:HF, cortisol and nephrines (two-way ANOVA; HTT by Day). Relative to LTHA, POST results differed significantly for Tc (Day 2, 6 and 9), HR (Day 2), logRMSSD (Day 2 and Day 6), logLF:HF (Day 2 and Day 6), cortisol (Day 2) and nephrines (Day 2 and Day 9). POST differences in HRV (Day 6 vs. 23) were + 9.9% (logRMSSD) and − 18.6% (logLF:HF).
Conclusions
Early reductions in HR and cortisol characterised STHA, whereas LTHA showed diminished excitability by Tc, HRV and nephrine measures. Measurement of HRV may have potential to aid real-time assessment of readiness for activity in the heat.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29127509</pmid><doi>10.1007/s00421-017-3758-y</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-5086-9025</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | European journal of applied physiology, 2018-01, Vol.118 (1), p.165-174 |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Acclimatization Adrenal glands Adult Autonomic Nervous System - physiology Biomedical and Life Sciences Biomedicine Cortisol Excitability Exercise Tolerance Heart Rate Heat tolerance Hormones Hot Temperature Human Physiology Humans Hydrocortisone - blood Male Membrane Proteins - blood Military Personnel Occupational Medicine/Industrial Medicine Original Original Article Sports Medicine Sympathetic nervous system Thermal injury |
| title | Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status |
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