Imaging short‐lived reactive oxygen species (ROS) with endogenous contrast MRI

Purpose To characterize the relaxation properties of reactive oxygen species (ROS) for the development of endogenous ROS contrast magnetic resonance imaging (MRI). Materials and Methods ROS‐producing phantoms and animal models were imaged at 9.4T MRI to obtain T1 and T2 maps. Egg white samples treat...

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Veröffentlicht in:	Journal of magnetic resonance imaging 2018-01, Vol.47 (1), p.222-229
Hauptverfasser:	Tain, Rong‐Wen, Scotti, Alessandro M., Li, Weiguo, Zhou, Xiaohong Joe, Cai, Kejia
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumen Animal models Animals Bovine serum albumin Brain Brain - diagnostic imaging Contrast Media - chemistry Disease Models, Animal Egg White - chemistry Feasibility studies free radicals Gadolinium Gadolinium DTPA Hydrogen peroxide Hydrogen Peroxide - pharmacology Hydrogen-Ion Concentration Hydroxyl Radical Image Enhancement Magnetic Resonance Imaging Male Mice MRI Neuroimaging NMR Nuclear magnetic resonance Oxygen Oxygen - chemistry paramagnetic effect pH effects Phantoms, Imaging Production methods Reactive oxygen species Reactive Oxygen Species - chemistry Reduction Relaxation time Reproducibility of Results Rotenone Rotenone - pharmacology Sensitivity Sensitivity and Specificity Serum albumin Serum Albumin, Bovine - chemistry Temperature
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