Intracellular trafficking of TREM2 is regulated by presenilin 1

Genetic mutations in triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to a variety of neurodegenerative diseases including Alzheimer’s disease, amyotrophic lateral sclerosis, frontotemporal dementia and Parkinson’s disease. In the brain, TREM2 is highly expressed on the cell...

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Veröffentlicht in:	Experimental & molecular medicine 2017-12, Vol.49 (12), p.e405-e405
Hauptverfasser:	Zhao, Yingjun, Li, Xiaoguang, Huang, Timothy, Jiang, Lu-lin, Tan, Zhenqiu, Zhang, Muxian, Cheng, Irene Han-Juo, Wang, Xin, Bu, Guojun, Zhang, Yun-wu, Wang, Qi, Xu, Huaxi
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/109 13/31 13/44 13/89 42/70 45/77 631/378/340 631/80/2023 82/29 82/80 Biomedical and Life Sciences Biomedicine Medical Biochemistry Molecular Medicine Original original-article Stem Cells
Online-Zugang:	Volltext
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