Mycophenolate mofetil modifies kidney tubular injury and Foxp3+ regulatory T cell trafficking during recovery from experimental ischemia–reperfusion

Abstract Lymphocytes participate in the early pathogenesis of ischemia–reperfusion injury (IRI) in kidney; however, their role during repair is largely unknown. Recent data have shown that Foxp3+ regulatory T cells (Tregs) traffic into kidney during healing from IRI and directly participate in repai...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Transplant immunology 2010-05, Vol.23 (1), p.45-52
Hauptverfasser:	Gandolfo, Maria Teresa, Jang, Hye Ryoun, Bagnasco, Serena M, Ko, Gang-Jee, Agreda, Patricia, Soloski, Mark J, Crow, Michael T, Rabb, Hamid
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Disease Models, Animal Forkhead Transcription Factors - metabolism Immunosuppressive Agents - therapeutic use Ischemia–reperfusion injury Kidney Kidney - drug effects Kidney - pathology Kidney Tubular Necrosis, Acute - drug therapy Kidney Tubular Necrosis, Acute - pathology Lymphocyte Male Mice Mice, Inbred C57BL Mice, Knockout Mycophenolate mofetil Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Repair Reperfusion Injury - drug therapy Reperfusion Injury - therapy T-Lymphocytes, Regulatory - cytology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!