Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

Translation initiation generally occurs at AUG codons in eukaryotes, although it has been shown that non-AUG or noncanonical translation initiation can also occur. However, the evidence for noncanonical translation initiation sites (TISs) is largely indirect and based on ribosome profiling (Ribo-seq...

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Veröffentlicht in:	Genome research 2018-01, Vol.28 (1), p.25-36
Hauptverfasser:	Na, Chan Hyun, Barbhuiya, Mustafa A, Kim, Min-Sik, Verbruggen, Steven, Eacker, Stephen M, Pletnikova, Olga, Troncoso, Juan C, Halushka, Marc K, Menschaert, Gerben, Overall, Christopher M, Pandey, Akhilesh
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions Amino acids Codons Conserved sequence Mass spectroscopy Methionine Open reading frames Proteins Translation Translation initiation
Online-Zugang:	Volltext
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