Suppression of microRNA-130b inhibits glioma cell proliferation and invasion, and induces apoptosis by PTEN/AKT signaling

Glioblastoma is the most common malignant brain tumor in adults and is characterized by extensive proliferation and the diffused invasion of tumor cells. Due to the intricate signaling pathways involved in glioma progression, more effective targeted therapies and prognostic biomarkers in clinical pr...

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Veröffentlicht in:	International journal of molecular medicine 2018-01, Vol.41 (1), p.284-292
Hauptverfasser:	Gu, Jian-Jun, Fan, Kai-Chun, Zhang, Jian-He, Chen, Hong-Jie, Wang, Shou-Sen
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Brain cancer Brain research Care and treatment Cell cycle Cell growth Cellular signal transduction Chemotherapy Development and progression Gene expression Genetic aspects Glioma Gliomas Health aspects Kinases Medical prognosis MicroRNA MicroRNAs Pancreatic cancer Phosphatase Phosphorylation Tumorigenesis
Online-Zugang:	Volltext
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