Emerging role of Hippo signalling pathway in bladder cancer

Bladder cancer (BC) is one of the most common cancers worldwide with a high progression rate and poor prognosis. The Hippo signalling pathway is a conserved pathway that plays a crucial role in cellular proliferation, differentiation and apoptosis. Furthermore, dysregulation and/or malfunction of th...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2018-01, Vol.22 (1), p.4-15
Hauptverfasser:	Xia, Jianling, Zeng, Ming, Zhu, Hua, Chen, Xiangjian, Weng, Zhiliang, Li, Shi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Bladder cancer Cancer Carcinogenesis - metabolism Carcinogenesis - pathology Chemoresistance dysregulation Hippo pathway Humans Metastases Models, Biological Protein-Serine-Threonine Kinases - metabolism Review Reviews Signal Transduction TAZ therapeutic target Tumors Urinary bladder Urinary Bladder Neoplasms - metabolism YAP1 Yes-associated protein
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